Diabetes and Cannabinoid CB1 receptor deficiency promote similar early onset aging-like changes in the skin

EC Leal, LIF Moura, RM Pirzgalska… - Experimental …, 2021 - Elsevier
Background The cannabinoid receptor type-1 (CB 1 R) is a major regulator of metabolism,
growth and inflammation. Yet, its potential role in the skin is not well understood. Our aim …

Revisiting CB1 cannabinoid receptor detection and the exploration of its interacting partners

PF Esteban, D Garcia-Ovejero… - Journal of Neuroscience …, 2020 - Elsevier
Abstract Background Cannabinoid receptor 1 (CB 1) identification by western blot (WB) has
generated a great deal of controversial data making the interpretation of the results difficult …

The combined ameliorative effects of α-lipoic acid, selenium, and vitamin E on the livers of STZ-diabetic mice

AK Kaçar, O Ertik, ZM Coşkun, S Bolkent… - İstanbul Journal of …, 2023 - dergipark.org.tr
Background and Aims: The aim of this study was to investigate the histological and
biochemical effects of the antioxidant combination on liver tissue of streptozotocin (STZ) …

[PDF][PDF] Effect of diet and physical exercise on endocannabinoid system and energy homeostasis in obese mice

F Ju, X Zhu, G Zhao, Q Yang - Int. J. Clin. Exp. Med, 2021 - e-century.us
This study investigated whether a combination of diet and exercise could improve
endocannabinoid system (ECS) and related-energy homeostasis during weight loss in …

Transient gain of function of cannabinoid CB1 receptors in the control of frontocortical glucose consumption in a rat model of Type-1 diabetes

JR Pedro, LIF Moura, Â Valério-Fernandes… - Brain research …, 2020 - Elsevier
Here we aimed to unify some previous controversial reports on changes in both cannabinoid
CB 1 receptor (CB 1 R) expression and glucose metabolism in the forebrain of rodent …

Type 2 Diabetes Alters Vascular Cannabinoid Receptor 1 Expression, Phosphorylation Status, and Vasorelaxation in Rat Aorta

E Sánchez-Pastor, X Trujillo, C Ramos-Flores… - Molecules, 2020 - mdpi.com
Previous studies have suggested a role of the endocannabinoid system in metabolic
diseases, such as diabetes. We investigated the effect of diabetes on cannabinoid receptor …