[HTML][HTML] Knee osteoarthritis: a review of pathogenesis and state-of-the-art non-operative therapeutic considerations
Being the most common musculoskeletal progressive condition, osteoarthritis is an
interesting target for research. It is estimated that the prevalence of knee osteoarthritis (OA) …
interesting target for research. It is estimated that the prevalence of knee osteoarthritis (OA) …
[HTML][HTML] Benefits and mechanisms of exercise training for knee osteoarthritis
CY Zeng, ZR Zhang, ZM Tang, FZ Hua - Frontiers in physiology, 2021 - frontiersin.org
Knee osteoarthritis is a chronic degenerative disease. Cartilage and subchondral bone
degeneration, as well as synovitis, are the main pathological changes associated with knee …
degeneration, as well as synovitis, are the main pathological changes associated with knee …
Knee osteoarthritis has doubled in prevalence since the mid-20th century
Knee osteoarthritis (OA) is believed to be highly prevalent today because of recent
increases in life expectancy and body mass index (BMI), but this assumption has not been …
increases in life expectancy and body mass index (BMI), but this assumption has not been …
Exercise as medicine–evidence for prescribing exercise as therapy in 26 different chronic diseases
BK Pedersen, B Saltin - … journal of medicine & science in sports, 2015 - Wiley Online Library
This review provides the reader with the up‐to‐date evidence‐based basis for prescribing
exercise as medicine in the treatment of 26 different diseases: psychiatric diseases …
exercise as medicine in the treatment of 26 different diseases: psychiatric diseases …
[HTML][HTML] Selenophosphate synthetase 1 deficiency exacerbates osteoarthritis by dysregulating redox homeostasis
D Kang, J Lee, J Jung, BA Carlson, MJ Chang… - Nature …, 2022 - nature.com
Aging and mechanical overload are prominent risk factors for osteoarthritis (OA), which lead
to an imbalance in redox homeostasis. The resulting state of oxidative stress drives the …
to an imbalance in redox homeostasis. The resulting state of oxidative stress drives the …
[HTML][HTML] Knee extensor muscle weakness is a risk factor for development of knee osteoarthritis. A systematic review and meta-analysis
The objective of this study was to perform a systematic review and meta-analysis on the
association between knee extensor muscle weakness and the risk of developing knee …
association between knee extensor muscle weakness and the risk of developing knee …
Osteolysis around total knee arthroplasty: a review of pathogenetic mechanisms
J Gallo, SB Goodman, YT Konttinen, MA Wimmer… - Acta biomaterialia, 2013 - Elsevier
Aseptic loosening and other wear-related complications are some of the most frequent late
reasons for revision of total knee arthroplasty (TKA). Periprosthetic osteolysis (PPOL) pre …
reasons for revision of total knee arthroplasty (TKA). Periprosthetic osteolysis (PPOL) pre …
Establishing outcome measures in early knee osteoarthritis
CA Emery, JL Whittaker, A Mahmoudian… - Nature Reviews …, 2019 - nature.com
The classification and monitoring of individuals with early knee osteoarthritis (OA) are
important considerations for the design and evaluation of therapeutic interventions and …
important considerations for the design and evaluation of therapeutic interventions and …
Post-traumatic osteoarthritis: from mouse models to clinical trials
Osteoarthritis (OA), the most common of all arthropathies, is a leading cause of disability and
has a large (and growing) worldwide socioeconomic cost. Despite its burgeoning …
has a large (and growing) worldwide socioeconomic cost. Despite its burgeoning …
Biological aspects of early osteoarthritis
Purpose Early OA primarily affects articular cartilage and involves the entire joint, including
the subchondral bone, synovial membrane, menisci and periarticular structures. The aim of …
the subchondral bone, synovial membrane, menisci and periarticular structures. The aim of …