Multimorbidity, commonly defined as the presence of two or more chronic medical conditions
in an individual, 1 is associated with decreased quality of life, functional decline, and …

Background Many people with chronic disease have more than one chronic condition, which
is referred to as multimorbidity. The term comorbidity is also used but this is now taken to …

Chronic pain is one of the most common conditions encountered by healthcare
professionals, particularly among older (≥ 65 years) patients. 1 Pain is associated with …

Background Common mental health problems, such as depression and anxiety, are
estimated to affect up to 15% of the UK population at any one time, and health care systems …

There is a bidirectional relationship between depression and chronic medical disorders. The
adverse health risk behaviors and psychobiological changes associated with depression …

Importance Persistent pain is highly prevalent, costly, and frequently disabling in later life.
Objective To describe barriers to the management of persistent pain among older adults …

Background Anxiety and depression are common psychological comorbidities that impact
the quality of life (QoL) of patients. In this systematic review, we 1) determined the impact of …

Osteoarthritis is a prevalent and debilitating disease that involves pathological contributions
from numerous joint tissues and cells. The joint is a challenging arena for drug delivery …

In addition to recurrent pain, fatigue, and increased rates of physical disability, individuals
with rheumatoid arthritis (RA) have an increased prevalence of some mental health …

BACKGROUND: Primary care patients with anxiety and depression often describe multiple
physical symptoms, but no systematic review has studied the effect of anxiety and …