Testicular torsion in vivo models: Mechanisms and treatments

A Minas, S Mahmoudabadi, NS Gamchi… - …, 2023 - Wiley Online Library
Background Testicular torsion is a condition in which a testis rotates around its longitudinal
axis and twists the spermatic cord. This in turn results in a significant decrease in blood flow …

Pathophysiology and management of testicular ischemia/reperfusion injury: Lessons from animal models

RE Akhigbe, AF Odetayo, TM Akhigbe, MA Hamed… - Heliyon, 2024 - cell.com
Testicular torsion is a urological emergency that involves the twisting of the spermatic cord
along its course. Compelling pieces of evidence have implicated oxidative stress-sensitive …

Spirulina platensis alleviates chronic inflammation with modulation of gut microbiota and intestinal permeability in rats fed a high‐fat diet

T Yu, Y Wang, X Chen, W Xiong… - Journal of cellular and …, 2020 - Wiley Online Library
Recent research suggested that taking a high‐fat diet (HFD) may lead to a gut microbiota
imbalance and colon tissue damage. This would lead to increased intestinal permeability …

Idebenone regulates sirt1/Nrf2/TNF-α pathway with inhibition of oxidative stress, inflammation, and apoptosis in testicular torsion/detorsion in juvenile rats

WY Abdelzaher, G Mostafa-Hedeab… - Human & …, 2022 - journals.sagepub.com
Testicular torsion is an emergency, mainly in newborn and adolescent males, resulting in
testicular ischemia. The current study aimed to evaluate the effect of Idebenone (IDE) on …

[HTML][HTML] Medical perspective in testicular ischemia‑reperfusion injury

S Arena, R Iacona, P Antonuccio… - Experimental and …, 2017 - spandidos-publications.com
Testicular torsion or torsion of the spermatic cord is one of the most serious urological
conditions. It causes testicular injury, which potentially leads to male subfertility. The turning …

Resolvins protect against diabetes‐induced colonic oxidative stress, barrier dysfunction, and associated diarrhea via the HO‐1 pathway

T Yu, D Chen, H Qi, L Lin, Y Tang - BioFactors, 2024 - Wiley Online Library
Diabetes is associated with increased oxidative stress, leading to altered tight junction
formation and increased apoptosis in colonic epithelial cells. These changes may lead to …

The protective effect of selenium on chronic zearalenone-induced reproductive system damage in male mice

M Long, S Yang, Y Wang, P Li, Y Zhang, S Dong… - Molecules, 2016 - mdpi.com
This study aims to explore the protective effect of selenium (Se) on chronic zearalenone
(ZEN)-induced reproductive system damage in male mice and the possible protective …

Involvement of hypoxia-inducible factor 1-α in experimental testicular ischemia and reperfusion: effects of polydeoxyribonucleotide and selenium

P Antonuccio, G Pallio, HR Marini, N Irrera… - International Journal of …, 2022 - mdpi.com
Polydeoxyribonucleotide (PDRN) is an agonist of the A2A adenosine receptor derived from
salmon trout sperm. Selenium (Se) is a trace element normally present in the diet. We aimed …

[HTML][HTML] Evaluation of vitamin C supplementation on kidney function and vascular reactivity following renal ischemic injury in mice

YB Zhu, YP Zhang, J Zhang, YB Zhang - Kidney and Blood Pressure …, 2016 - karger.com
Background/Aims: Renal ischemia/reperfusion injury (IRI) is a very common clinical event
and usually leads to ischemic acute renal failure (ARF). In the present study, we investigated …

[PDF][PDF] Role of antioxidants in preventing testicular ischemia‑reperfusion injury: a narrative review.

ZM Li - European Review for Medical & Pharmacological …, 2022 - europeanreview.org
Testicular ischemia-reperfusion injury (TIR) is a urological emergency common among male
newborns, children, and adolescents. Testicular injury and its consequences, such as …