Nonviral In Vivo Delivery of CRISPR-Cas9 Using Protein-Agnostic, High-Loading Porous Silicon and Polymer Nanoparticles
RB Fletcher, LD Stokes, IB Kelly III, KM Henderson… - ACS …, 2023 - ACS Publications
The complexity of CRISPR machinery is a challenge to its application for nonviral in vivo
therapeutic gene editing. Here, we demonstrate that proteins, regardless of size or charge …
therapeutic gene editing. Here, we demonstrate that proteins, regardless of size or charge …
Ligand-based surface engineering of nanomaterials: Trends, challenges, and biomedical perspectives
Biomedical applications of nanomaterials, especially in diagnosing, management, and
treatment of-diseases are evolving. However, nanotoxicity remains a major challenge in …
treatment of-diseases are evolving. However, nanotoxicity remains a major challenge in …
Nanoporous quercetin-loaded silicon-stabilized hybrid lipid nanoparticles alleviate salt stress in tomato plants
G Guerriero, FM Sutera, J Hoffmann… - ACS Applied Nano …, 2023 - ACS Publications
The search for more effective methods to alleviate the negative effects of exogenous
stresses in plants has inspired nanotechnologies. It is in this context that the use of …
stresses in plants has inspired nanotechnologies. It is in this context that the use of …
[HTML][HTML] APTES-Based Silica Nanoparticles as a Potential Modifier for the Selective Sequestration of CO2 Gas Molecules
EJ Cueto-Díaz, A Castro-Muñiz, F Suárez-García… - Nanomaterials, 2021 - mdpi.com
In this work, we have described the characterization of hybrid silica nanoparticles of 50 nm
size, showing outstanding size homogeneity, a large surface area, and remarkable CO2 …
size, showing outstanding size homogeneity, a large surface area, and remarkable CO2 …
Design of scaffolds based on zinc-modified marine collagen and bilberry leaves extract-loaded silica nanoparticles as wound dressings
Purpose In this study, wound dressings were designed using zinc-modified marine collagen
porous scaffold as host for wild bilberry (WB) leaves extract immobilized in functionalized …
porous scaffold as host for wild bilberry (WB) leaves extract immobilized in functionalized …
Cell penetrating peptide decorated magnetic porous silicon nanorods for glioblastoma therapy and imaging
A Chaix, A Griveau, T Defforge, V Grimal… - RSC …, 2022 - pubs.rsc.org
Glioblastoma multiforme (GBM) is the most malignant primary brain tumor of the central
nervous system. Despite advances in therapy, it remains largely untreatable, in part due to …
nervous system. Despite advances in therapy, it remains largely untreatable, in part due to …
CO2 adsorption capacities of amine-functionalized microporous silica nanoparticles
EJ Cueto-Díaz, F Suárez-García… - Reactive and Functional …, 2022 - Elsevier
Efforts on CO 2 capture have intensified as climate change compromises ecosystems and
biodiversity. Therefore, it is crucial to develop different methods for CO 2 sequestration to …
biodiversity. Therefore, it is crucial to develop different methods for CO 2 sequestration to …
Tuning composition of polymer and porous Silicon Composite nanoparticles for early endosome escape of Anti-microRNA peptide nucleic acids
Porous silicon nanoparticles (PSNPs) offer tunable pore structure and easily modified
surface chemistry, enabling high loading capacity for drugs with diverse chemicophysical …
surface chemistry, enabling high loading capacity for drugs with diverse chemicophysical …
Amino acid-metal phosphate hybrid nanoflowers (AaHNFs): their preparation, characterization and anti-oxidant capacities
N Özdemir, C Altinkaynak, M Türk, F Geçili… - Polymer Bulletin, 2022 - Springer
Reactive oxygen species like hydrogen peroxide have positive roles in vivo systems such as
phagocytosis, intercellular signal transfer, regulation of cell growth, and the synthesis of …
phagocytosis, intercellular signal transfer, regulation of cell growth, and the synthesis of …
Recent progress on nanosystems for nucleic acid delivery
Nucleic acid (NA)-based therapeutics have witnessed tremendous progress and
breakthroughs in treating pathological conditions, including viral infections, neurological …
breakthroughs in treating pathological conditions, including viral infections, neurological …