Mechanism of action and biology of flow diverters in the treatment of intracranial aneurysms

K Ravindran, AM Casabella, J Cebral, W Brinjikji… - …, 2020 - journals.lww.com
Flow diverters have drastically changed the landscape of intracranial aneurysm treatment
and are now considered first-line therapy for select lesions. Their mechanism of action relies …

North American multicenter experience with the Flow Redirection Endoluminal Device in the treatment of intracranial aneurysms

MH Khorasanizadeh, M Shutran, CM Schirmer… - Journal of …, 2022 - thejns.org
OBJECTIVE Flow diverters have revolutionized the endovascular treatment of intracranial
aneurysms. Here, the authors present the first large-scale North American multicenter …

Endothelial Progenitor Cells: A Review of Molecular Mechanisms in the Pathogenesis and Endovascular Treatment of Intracranial Aneurysms

F Ramirez-Velandia, E Mensah, M Salih… - NeuroMolecular …, 2024 - Springer
This comprehensive review explores the multifaceted role of endothelial progenitor cells
(EPCs) in vascular diseases, focusing on their involvement in the pathogenesis and their …

[HTML][HTML] Reduced thrombogenicity of surface-treated Nitinol implants steered by altered protein adsorption

K Gegenschatz-Schmid, S Buzzi, J Grossmann… - Acta Biomaterialia, 2022 - Elsevier
Blood-contacting medical implants made of Nitinol and other titanium alloys, such as
neurovascular flow diverters and peripheral stents, have the disadvantage of being highly …

The first decade of flow diversion for intracranial aneurysms with the Pipeline embolization device

A Monteiro, J Lim, M Siddiqi, BM Donnelly… - Neurosurgical …, 2023 - thejns.org
OBJECTIVE Flow diverter devices have revolutionized the treatment of intracranial
aneurysms (IAs) since their approval in 2011 and have continued to evolve. The devices …

Small and medium-sized aneurysm outcomes following intracranial aneurysm treatment using the pipeline embolization device: a subgroup analysis of the PLUS …

H Zhang, L Li, H Zhang, J Liu, D Song, Y Zhao… - Frontiers in …, 2022 - frontiersin.org
Objective The purpose of this work was to summarize the real-world safety and efficacy of
Pipeline Embolization Device (PED) therapy for small and medium-sized intracranial …

Effect of flow diverter stent malposition on intracranial aneurysm hemodynamics—an experimental framework using stereoscopic particle image velocimetry

C Roloff, P Berg - Plos one, 2022 - journals.plos.org
Background Flow-diverting stents are increasingly used for the minimally-invasive treatment
of intracranial aneurysms. However, a correct positioning of such devices can be …

Predictors of aneurysmal occlusion following intracranial aneurysms treatment with pipeline embolization device

MM Salem, MH Khorasanizadeh, F Nwajei… - Acta …, 2023 - Springer
Purpose Pipeline embolization device (PED) is thought to induce aneurysmal occlusion
through diversion of flow away from the aneurysmal sac with subsequent thrombosis and …

Safety and efficacy of the off-label use of pipeline embolization device based on the 2018 Food and Drug Administration-approved indications for intracranial …

A Enriquez-Marulanda, A Penumaka, CS Ogilvy… - …, 2022 - journals.lww.com
BACKGROUND: The pipeline embolization device (PED; ev3/Covidien) has proven safe
and effective for treating selected intracranial aneurysms. This device's versatility and …

In vitro Implementation of Photopolymerizable Hydrogels as a Potential Treatment of Intracranial Aneurysms

O Poupart, A Schmocker, R Conti, C Moser… - … in bioengineering and …, 2020 - frontiersin.org
Intracranial aneurysms are increasingly being treated with endovascular therapy, namely
coil embolization. Despite being minimally invasive, partial occlusion and recurrence are …