Biological activity of plant-based carvacrol and thymol and their impact on human health and food quality

NB Rathod, P Kulawik, F Ozogul, JM Regenstein… - Trends in Food Science …, 2021 - Elsevier
Background There is an increased consumer demand for products derived from natural
sources or containing natural compounds used to preserve or improve food quality and/or …

Therapeutic application of carvacrol: A comprehensive review

M Imran, M Aslam, SA Alsagaby, F Saeed… - Food science & …, 2022 - Wiley Online Library
Carvacrol is a major natural constituent and is significantly present as an essential oil in
aromatic plants and is well known for its numerous biological activities. Therapeutic …

[HTML][HTML] Polychemotherapy with curcumin and doxorubicin via biological nanoplatforms: enhancing antitumor activity

M Ashrafizadeh, A Zarrabi, F Hashemi, A Zabolian… - Pharmaceutics, 2020 - mdpi.com
Doxorubicin (DOX) is a well-known chemotherapeutic agent extensively applied in the field
of cancer therapy. However, similar to other chemotherapeutic agents such as cisplatin …

Monoterpenes and their derivatives as agents for cardiovascular disease management: A systematic review and meta-analysis

EAP Silva, DM Santos, FO de Carvalho, IAC Menezes… - Phytomedicine, 2021 - Elsevier
Background Monoterpenes are one of the most studied plant's secondary metabolites, they
are found abundantly in essential oils of aromatic plants. They also have a great range of …

Protective effects of carvacrol on lipid profiles, oxidative stress, hypertension, and cardiac dysfunction–A comprehensive review

MR Khazdair, M Moshtagh… - Food Science & …, 2024 - Wiley Online Library
Cardiovascular diseases (CVDs) are a class of illnesses that affect the heart or blood
vessels, leading to the most common causes of death worldwide. In 2017, CVD caused …

[HTML][HTML] 1, 8-Cineole ameliorates right ventricle dysfunction associated with pulmonary arterial hypertension by restoring connexin43 and mitochondrial homeostasis

JM Alves-Silva, M Zuzarte, C Marques, S Viana… - Pharmacological …, 2022 - Elsevier
For the first time, the present study unravels a cardiospecific therapeutic approach for
Pulmonary Arterial Hypertension (PAH), a disease with a very poor prognosis and high …

Carvacrol and its effect on cardiovascular diseases: From molecular mechanism to pharmacological modulation

V Garg, BD Sahu - Food Bioscience, 2024 - Elsevier
Cardiovascular diseases (CVDs) affect worldwide and influence people from diverse
cultures, socioeconomic status, ethnicities, and healthcare systems. The underlying …

Effect of treatment with carvacrol and aerobic training on cardiovascular function in spontaneously hypertensive rats

HA Costa, CJM Dias, VA Martins… - Experimental …, 2021 - Wiley Online Library
New Findings What is the central question of this study? Can two non‐drug therapies,
carvacrol and aerobic physical training, together have additive effects on the reduction of …

The effects of carvacrol on oxidative stress, inflammation, and liver function indicators in a systemic inflammation model induced by lipopolysaccharide in rats

A Mortazavi, HMP Kargar, F Beheshti… - … Journal for Vitamin …, 2021 - econtent.hogrefe.com
The effect of carvacrol (CAR) on oxidative stress, inflammation, and liver dysfunction
induced by lipopolysaccharide (LPS) was explored. The rats (n= 40) were daily injected (2 …

The Protective Effects of Carvacrol Against Doxorubicin-Induced Cardiotoxicity In Vitro and In Vivo

R Retnosari, MA Abdul Ghani, M Majed Alkharji… - Cardiovascular …, 2024 - Springer
Doxorubicin (DOX) is a remarkable chemotherapeutic agent, however, its adverse effect on
DOX-induced cardiotoxicity (DIC) is a rising concern. Recent research has identified …