Trans-synaptic Association of Vesicular Zinc Transporter 3 and Shank3 Supports Synapse-Specific Dendritic Spine Structure and Function in the Mouse Auditory …

A Manning, PTR Bender, H Boyd-Pratt… - Journal of …, 2024 - jneurosci.org
Shank3 is a synaptic scaffolding protein that assists in tethering and organizing structural
proteins and glutamatergic receptors in the postsynaptic density of excitatory synapses. The …

Cell-type-specific enhancement of deviance detection by synaptic zinc in the mouse auditory cortex

M McCollum, A Manning, PTR Bender… - Proceedings of the …, 2024 - pnas.org
Stimulus-specific adaptation is a hallmark of sensory processing in which a repeated
stimulus results in diminished successive neuronal responses, but a deviant stimulus will …

Tafluprost promotes axon regeneration after optic nerve crush via Zn2+-mTOR pathway

S Wu, C Liu, J Tang, C Wu, Q Zhang, Z Liu, J Han… - …, 2024 - Elsevier
Abstract Purpose To investigate whether Tafluprost could promote optic nerve regeneration
in mice after optic nerve crush (ONC) and determine the underlying molecular mechanism …

Cortical Zinc Signaling Is Necessary for Changes in Mouse Pupil Diameter That Are Evoked by Background Sounds with Different Contrasts

P Cody, M Kumar, T Tzounopoulos - Journal of Neuroscience, 2024 - Soc Neuroscience
Luminance-independent changes in pupil diameter (PD) during wakefulness influence and
are influenced by neuromodulatory, neuronal, and behavioral responses. However, it is …

The role of synaptic zinc signaling in excitatory circuits of the mouse auditory cortex

PTR Bender - 2024 - researchrepository.wvu.edu
Synaptic zinc signaling modulates synaptic activity and is present in specific populations of
cortical neurons, suggesting that synaptic zinc contributes to the diversity of intracortical …