Sirtuins' control of autophagy and mitophagy in cancer
M Aventaggiato, E Vernucci, F Barreca… - Pharmacology & …, 2021 - Elsevier
Mammalian cells use a specialized and complex machinery for the removal of altered
proteins or dysfunctional organelles. Such machinery is part of a mechanism called …
proteins or dysfunctional organelles. Such machinery is part of a mechanism called …
Autophagy-regulating microRNAs and cancer
Macroautophagy (autophagy herein) is a cellular stress response and a survival pathway
that is responsible for the degradation of long-lived proteins, protein aggregates, as well as …
that is responsible for the degradation of long-lived proteins, protein aggregates, as well as …
Immunosuppressive effects of hypoxia-induced glioma exosomes through myeloid-derived suppressor cells via the miR-10a/Rora and miR-21/Pten Pathways
X Guo, W Qiu, Q Liu, M Qian, S Wang, Z Zhang, X Gao… - Oncogene, 2018 - nature.com
While immunosuppressive environments mediated by myeloid-derived suppressor cells
(MDSCs) have been well documented in glioma patients, the mechanisms of MDSC …
(MDSCs) have been well documented in glioma patients, the mechanisms of MDSC …
A novel tumor-promoting mechanism of IL6 and the therapeutic efficacy of tocilizumab: Hypoxia-induced IL6 is a potent autophagy initiator in glioblastoma via the p …
H Xue, G Yuan, X Guo, Q Liu, J Zhang, X Gao, X Guo… - Autophagy, 2016 - Taylor & Francis
Hypoxia induces protective autophagy in glioblastoma cells and new therapeutic avenues
that target this process may improve the outcome for glioblastoma patients. Recent studies …
that target this process may improve the outcome for glioblastoma patients. Recent studies …
Autophagy as a potential therapy for malignant glioma
A Escamilla-Ramírez, RA Castillo-Rodríguez… - Pharmaceuticals, 2020 - mdpi.com
Glioma is the most frequent and aggressive type of brain neoplasm, being anaplastic
astrocytoma (AA) and glioblastoma multiforme (GBM), its most malignant forms. The survival …
astrocytoma (AA) and glioblastoma multiforme (GBM), its most malignant forms. The survival …
Pyroptosis, ferroptosis, and autophagy cross-talk in glioblastoma opens up new avenues for glioblastoma treatment
S Wan, G Zhang, R Liu, MN Abbas, H Cui - Cell Communication and …, 2023 - Springer
Glioma is a common primary tumor of the central nervous system (CNS), with glioblastoma
multiforme (GBM) being the most malignant, aggressive, and drug resistant. Most drugs are …
multiforme (GBM) being the most malignant, aggressive, and drug resistant. Most drugs are …
Emerging connections between RNA and autophagy
LB Frankel, M Lubas, AH Lund - Autophagy, 2017 - Taylor & Francis
Macroautophagy/autophagy is a key catabolic process, essential for maintaining cellular
homeostasis and survival through the removal and recycling of unwanted cellular material …
homeostasis and survival through the removal and recycling of unwanted cellular material …
Novel role of miR-133a-3p in repressing gastric cancer growth and metastasis via blocking autophagy-mediated glutaminolysis
X Zhang, Z Li, Z Xuan, P Xu, W Wang, Z Chen… - Journal of Experimental …, 2018 - Springer
Background Autophagy plays a crucial role in sustaining the homeostasis in various
malignant diseases. It has also been reported to promote tumor development in multiple …
malignant diseases. It has also been reported to promote tumor development in multiple …
[HTML][HTML] MicroRNAs as major regulators of the autophagy pathway
Y Akkoc, D Gozuacik - Biochimica et Biophysica Acta (BBA)-Molecular Cell …, 2020 - Elsevier
Autophagy is a cellular stress response mechanism activation of which leads to degradation
of cellular components, including proteins as well as damaged organelles in lysosomes …
of cellular components, including proteins as well as damaged organelles in lysosomes …
MicroRNA as a therapeutic target in cardiac remodeling
C Chen, M Ponnusamy, C Liu, J Gao… - BioMed research …, 2017 - Wiley Online Library
MicroRNAs (miRNAs) are small RNA molecules that contain 18–25 nucleotides. The
alterations in their expression level play crucial role in the development of many disorders …
alterations in their expression level play crucial role in the development of many disorders …