Cancer progression is caused by genetic changes and associated with various alterations in
cell properties, which also affect a tumor's mechanical state. While an increased stiffness …

In cell clusters, the prominent factors at play encompass contractility-based enhanced tissue
surface tension and cell unjamming transition. The former effect pertains to the boundary …

Organoids are in vitro cellular collectives from which, for example, brain-like, or gut-like, or
kidney-like structures emerge. To make quantitative predictions regarding the morphology …

The hERG1 potassium channel is aberrantly over expressed in tumors and regulates the
cancer cell response to integrin-dependent adhesion. We unravel a novel signaling pathway …

Although a good comprehension of how cancer cells collectively migrate by following
molecular rules which influence the state of cell-cell adhesion contacts has been generated …

Skin cancer is the most commonly occurring cancer in the USA and Germany, and the fourth
most common cancer worldwide. Snail-dependent epithelial–mesenchymal transition (EMT) …

The growth and invasion of solid tumors are associated with changes in their viscoelastic
properties, influenced by both internal cellular factors and physical forces in the tumor …

Cells can adapt their active contractile properties to switch between dynamical migratory
states and static homeostasis. Collective tissue surface tension, generated among others by …

Integrin-based adhesion complexes are crucial in various cellular processes, including
proliferation, differentiation, and motility. While the dynamics of canonical focal adhesion …

How genes affect tissue scale organization remains a longstanding biological puzzle. As
experimental efforts are underway to solve this puzzle via quantification of gene expression …