Steps towards standardized quantification of adult neurogenesis
X Zhao, H van Praag - Nature communications, 2020 - nature.com
New neurons are generated in adult mammals. Adult hippocampal neurogenesis is
considered to play an important role in cognition and mental health. The number and …
considered to play an important role in cognition and mental health. The number and …
LLPS of FXR1 drives spermiogenesis by activating translation of stored mRNAs
JY Kang, Z Wen, D Pan, Y Zhang, Q Li, A Zhong, X Yu… - Science, 2022 - science.org
Postmeiotic spermatids use a unique strategy to coordinate gene expression with
morphological transformation, in which transcription and translation take place at separate …
morphological transformation, in which transcription and translation take place at separate …
Inhibition of glycogen synthase kinase 3 by lithium, a mechanism in search of specificity
D Chatterjee, JM Beaulieu - Frontiers in Molecular Neuroscience, 2022 - frontiersin.org
Inhibition of Glycogen synthase kinase 3 (GSK3) is a popular explanation for the effects of
lithium ions on mood regulation in bipolar disorder and other mental illnesses, including …
lithium ions on mood regulation in bipolar disorder and other mental illnesses, including …
Widespread RNA editing dysregulation in brains from autistic individuals
SS Tran, HI Jun, JH Bahn, A Azghadi… - Nature …, 2019 - nature.com
Transcriptomic analyses of postmortem brains have begun to elucidate molecular
abnormalities in autism spectrum disorder (ASD). However, a crucial pathway involved in …
abnormalities in autism spectrum disorder (ASD). However, a crucial pathway involved in …
The multifaceted role of Fragile X-Related Protein 1 (FXR1) in cellular processes: an updated review on cancer and clinical applications
FA Khan, N Fang, W Zhang, S Ji - Cell Death & Disease, 2024 - nature.com
RNA-binding proteins (RBPs) modulate the expression level of several target RNAs (such as
mRNAs) post-transcriptionally through interactions with unique binding sites in the 3 …
mRNAs) post-transcriptionally through interactions with unique binding sites in the 3 …
RNA-binding protein signaling in adult neurogenesis
JNM Chan, DI Sánchez-Vidaña… - Frontiers in Cell and …, 2022 - frontiersin.org
The process of neurogenesis in the brain, including cell proliferation, differentiation, survival,
and maturation, results in the formation of new functional neurons. During embryonic …
and maturation, results in the formation of new functional neurons. During embryonic …
FXR1 regulation of parvalbumin interneurons in the prefrontal cortex is critical for schizophrenia-like behaviors
Parvalbumin interneurons (PVIs) are affected in many psychiatric disorders including
schizophrenia (SCZ), however the mechanism remains unclear. FXR1, a high confident risk …
schizophrenia (SCZ), however the mechanism remains unclear. FXR1, a high confident risk …
FXR1 splicing is important for muscle development and biomolecular condensates in muscle cells
Fragile-X mental retardation autosomal homologue-1 (FXR1) is a muscle-enriched RNA-
binding protein. FXR1 depletion is perinatally lethal in mice, Xenopus, and zebrafish; …
binding protein. FXR1 depletion is perinatally lethal in mice, Xenopus, and zebrafish; …
Acute oligodendrocyte loss with persistent white matter injury in a third trimester equivalent mouse model of fetal alcohol spectrum disorder
J Newville, CF Valenzuela, L Li, LL Jantzie… - Glia, 2017 - Wiley Online Library
Alcohol exposure during central nervous system (CNS) development can lead to fetal
alcohol spectrum disorder (FASD). Human imaging studies have revealed significant white …
alcohol spectrum disorder (FASD). Human imaging studies have revealed significant white …
Cell signaling in neuronal stem cells
The defining characteristic of neural stem cells (NSCs) is their ability to multiply through
symmetric divisions and proliferation, and differentiation by asymmetric divisions, thus giving …
symmetric divisions and proliferation, and differentiation by asymmetric divisions, thus giving …