Long intergenic non-coding RNA (lincRNA) genes have diverse features that distinguish
them from mRNA-encoding genes and exercise functions such as remodelling chromatin …

Genomes of multicellular organisms are characterized by the pervasive expression of
different types of non-coding RNAs (ncRNAs). Long ncRNAs (lncRNAs) belong to a novel …

The human genome contains many thousands of long noncoding RNAs (lncRNAs). While
several studies have demonstrated compelling biological and disease roles for individual …

Recent transcriptome studies have revealed that a large number of transcripts in mammals
and other organisms do not encode proteins but function as noncoding RNAs (ncRNAs) …

Recent RNA sequencing studies have revealed that most of the human genome is
transcribed, but very little of the total transcriptomes has the ability to encode proteins. Long …

From the earliest comparisons of RNA production with steady-state levels, it has been clear
that cells transcribe more RNA than they accumulate, implying the existence of active RNA …

Although accumulating evidence has provided insight into the various functions of long-non-
coding RNAs (lncRNAs), the exact functions of the majority of such transcripts are still …

Abstract Background Long non-coding RNAs (lncRNAs) are transcripts that are 200 bp or
longer, do not encode proteins, and potentially play important roles in eukaryotic gene …

Long transcripts that do not encode protein have only rarely been the subject of
experimental scrutiny. Presumably, this is owing to the current lack of evidence of their …

A fundamental goal of genomics is to identify the complete set of expressed proteins.
Automated annotation strategies rely on assumptions about protein-coding sequences …