Chemokines from a structural perspective
MC Miller, KH Mayo - International journal of molecular sciences, 2017 - mdpi.com
Chemokines are a family of small, highly conserved cytokines that mediate various
biological processes, including chemotaxis, hematopoiesis, and angiogenesis, and that …
biological processes, including chemotaxis, hematopoiesis, and angiogenesis, and that …
Applications of the phage display technology in molecular biology, biotechnology and medicine
K Pierzynowska, J Morcinek-Orłowska… - Critical Reviews in …, 2024 - Taylor & Francis
The phage display technology is based on the presentation of peptide sequences on the
surface of virions of bacteriophages. Its development led to creation of sophisticated systems …
surface of virions of bacteriophages. Its development led to creation of sophisticated systems …
Understanding the mechanisms that facilitate specificity, not redundancy, of chemokine‐mediated leukocyte recruitment
DP Dyer - Immunology, 2020 - Wiley Online Library
Chemokines (chemotactic cytokines) and their receptors are critical to recruitment and
positioning of cells during development and the immune response. The chemokine system …
positioning of cells during development and the immune response. The chemokine system …
Targeting chemokines: Pathogens can, why can't we?
AEI Proudfoot, P Bonvin, CA Power - Cytokine, 2015 - Elsevier
Chemoattractant cytokines, or chemokines, are the largest sub-family of cytokines. About 50
distinct chemokines have been identified in humans. Their principal role is to stimulate the …
distinct chemokines have been identified in humans. Their principal role is to stimulate the …
Ticks from diverse genera encode chemokine-inhibitory evasin proteins
To prolong residence on their hosts, ticks secrete many salivary factors that target host
defense molecules. In particular, the tick Rhipicephalus sanguineus has been shown to …
defense molecules. In particular, the tick Rhipicephalus sanguineus has been shown to …
Perspectives on the biological role of chemokine: glycosaminoglycan interactions
TM Handel, DP Dyer - Journal of Histochemistry & …, 2021 - journals.sagepub.com
Chemokines (chemotactic cytokines) are a family of proteins that mediate recruitment and
precise positioning of leukocytes in different anatomical locations, and as such are central to …
precise positioning of leukocytes in different anatomical locations, and as such are central to …
Evasins: tick salivary proteins that inhibit mammalian chemokines
RP Bhusal, JRO Eaton, ST Chowdhury… - Trends in biochemical …, 2020 - cell.com
Ticks are hematophagous arachnids that parasitize mammals and other hosts, feeding on
their blood. Ticks secrete numerous salivary factors that enhance host blood flow or …
their blood. Ticks secrete numerous salivary factors that enhance host blood flow or …
The tick and I: Parasite‐host interactions between ticks and humans
MP Schön - JDDG: Journal der Deutschen Dermatologischen …, 2022 - Wiley Online Library
Ticks, particularly hard ticks (Ixodidae), which are among the most important vectors of
dangerous infectious agents, feed on their hosts for extended periods of time. With this …
dangerous infectious agents, feed on their hosts for extended periods of time. With this …
Evasins: therapeutic potential of a new family of chemokine-binding proteins from ticks
P Bonvin, CA Power, AEI Proudfoot - Frontiers in immunology, 2016 - frontiersin.org
Blood-sucking parasites, such as ticks, remain attached to their hosts for relatively long
periods of time in order to obtain their blood meal without eliciting an immune response. One …
periods of time in order to obtain their blood meal without eliciting an immune response. One …
Yeast surface display identifies a family of evasins from ticks with novel polyvalent CC chemokine-binding activities
K Singh, G Davies, Y Alenazi, JRO Eaton… - Scientific reports, 2017 - nature.com
Chemokines function via G-protein coupled receptors in a robust network to recruit immune
cells to sites of inflammation. Due to the complexity of this network, targeting single …
cells to sites of inflammation. Due to the complexity of this network, targeting single …