Tumor immune microenvironment lncRNAs

EG Park, SJ Pyo, Y Cui, SH Yoon… - Briefings in …, 2022 - academic.oup.com
Long non-coding ribonucleic acids (RNAs)(lncRNAs) are key players in tumorigenesis and
immune responses. The nature of their cell type-specific gene expression and other …

[HTML][HTML] Long non-coding RNAs: from disease code to drug role

Y Chen, Z Li, X Chen, S Zhang - Acta Pharmaceutica Sinica B, 2021 - Elsevier
Enormous studies have corroborated that long non-coding RNAs (lncRNAs) extensively
participate in crucial physiological processes such as metabolism and immunity, and are …

Non-coding RNAs and potential therapeutic targeting in cancer

S Toden, TJ Zumwalt, A Goel - … et Biophysica Acta (BBA)-Reviews on …, 2021 - Elsevier
Recent advances have begun to clarify the physiological and pathological roles of non-
coding RNAs (ncRNAs) in various diseases, including cancer. Among these, microRNAs …

Therapeutic targeting of long non-coding RNAs in cancer

G Arun, SD Diermeier, DL Spector - Trends in molecular medicine, 2018 - cell.com
Long non-coding RNAs (lncRNAs) represent a significant population of the human
transcriptome. Many lncRNAs exhibit cell-and/or tissue/tumor-specific expression, making …

MicroRNAs (miRNAs) and long non-coding RNAs (lncRNAs) as new tools for cancer therapy: first steps from bench to bedside

M Ratti, A Lampis, M Ghidini, M Salati, MB Mirchev… - Targeted …, 2020 - Springer
Non-coding RNAs represent a significant proportion of the human genome. After having
been considered as 'junk'for a long time, non-coding RNAs are now well established as …

Non-coding RNAs: the new central dogma of cancer biology

PE Saw, X Xu, J Chen, EW Song - Science China Life Sciences, 2021 - Springer
The central dogma of molecular biology states that the functions of RNA revolve around
protein translation. Until the last decade, most researches were geared towards …

Long noncoding RNA and cancer: a new paradigm

A Bhan, M Soleimani, SS Mandal - Cancer research, 2017 - AACR
In addition to mutations or aberrant expression in the protein-coding genes, mutations and
misregulation of noncoding RNAs, in particular long noncoding RNAs (lncRNA), appear to …

[PDF][PDF] Oncofetal long noncoding RNA PVT1 promotes proliferation and stem cell‐like property of hepatocellular carcinoma cells by stabilizing NOP2

F Wang, JH Yuan, SB Wang, F Yang, SX Yuan… - …, 2014 - Wiley Online Library
Many protein‐coding oncofetal genes are highly expressed in murine and human fetal liver
and silenced in adult liver. The protein products of these hepatic oncofetal genes have been …

Long non-coding RNA H19 increases bladder cancer metastasis by associating with EZH2 and inhibiting E-cadherin expression

M Luo, Z Li, W Wang, Y Zeng, Z Liu, J Qiu - Cancer letters, 2013 - Elsevier
lncRNA H19 is essential for human tumor growth. However, little is known about whether
H19 regulates bladder cancer metastasis. Here we found that H19 levels are remarkably …

Targeting long non-coding RNAs in cancers: progress and prospects

CH Li, Y Chen - The international journal of biochemistry & cell biology, 2013 - Elsevier
Pervasive transcription occurs in the human genome to generate thousands of RNA
transcripts, and accumulating evidence suggested that the RNA molecules, without protein …