Quantifying brain microstructure with diffusion MRI: Theory and parameter estimation
We review, systematize and discuss models of diffusion in neuronal tissue, by putting them
into an overarching physical context of coarse‐graining over an increasing diffusion length …
into an overarching physical context of coarse‐graining over an increasing diffusion length …
Imaging brain microstructure with diffusion MRI: practicality and applications
This article gives an overview of microstructure imaging of the brain with diffusion MRI and
reviews the state of the art. The microstructure‐imaging paradigm aims to estimate and map …
reviews the state of the art. The microstructure‐imaging paradigm aims to estimate and map …
[HTML][HTML] Quantification of microscopic diffusion anisotropy disentangles effects of orientation dispersion from microstructure: applications in healthy volunteers and in …
The anisotropy of water diffusion in brain tissue is affected by both disease and
development. This change can be detected using diffusion MRI and is often quantified by the …
development. This change can be detected using diffusion MRI and is often quantified by the …
In vivo observation and biophysical interpretation of time-dependent diffusion in human white matter
The presence of micrometer-level restrictions leads to a decrease of diffusion coefficient with
diffusion time. Here we investigate this effect in human white matter in vivo. We focus on a …
diffusion time. Here we investigate this effect in human white matter in vivo. We focus on a …
Monte Carlo study of a two‐compartment exchange model of diffusion
Multisite exchange models have been applied frequently to quantify measurements of
transverse relaxation and diffusion in living tissues. Although the simplicity of such models is …
transverse relaxation and diffusion in living tissues. Although the simplicity of such models is …
[HTML][HTML] The sensitivity of diffusion MRI to microstructural properties and experimental factors
Diffusion MRI is a non-invasive technique to study brain microstructure. Differences in the
microstructural properties of tissue, including size and anisotropy, can be represented in the …
microstructural properties of tissue, including size and anisotropy, can be represented in the …
Towards unconstrained compartment modeling in white matter using diffusion‐relaxation MRI with tensor‐valued diffusion encoding
B Lampinen, F Szczepankiewicz… - Magnetic resonance …, 2020 - Wiley Online Library
Purpose To optimize diffusion‐relaxation MRI with tensor‐valued diffusion encoding for
precise estimation of compartment‐specific fractions, diffusivities, and T2 values within a two …
precise estimation of compartment‐specific fractions, diffusivities, and T2 values within a two …
Searching for the neurite density with diffusion MRI: challenges for biophysical modeling
B Lampinen, F Szczepankiewicz, M Novén… - Human brain …, 2019 - Wiley Online Library
In vivo mapping of the neurite density with diffusion MRI (dMRI) is a high but challenging
aim. First, it is unknown whether all neurites exhibit completely anisotropic (“stick‐like”) …
aim. First, it is unknown whether all neurites exhibit completely anisotropic (“stick‐like”) …
Noninvasive mapping of water diffusional exchange in the human brain using filter‐exchange imaging
We present the first in vivo application of the filter‐exchange imaging protocol for diffusion
MRI. The protocol allows noninvasive mapping of the rate of water exchange between …
MRI. The protocol allows noninvasive mapping of the rate of water exchange between …
[HTML][HTML] A test-retest study on Parkinson's PPMI dataset yields statistically significant white matter fascicles
In this work, we propose a diffusion MRI protocol for mining Parkinson's disease diffusion
MRI datasets and recover robust disease-specific biomarkers. Using advanced high angular …
MRI datasets and recover robust disease-specific biomarkers. Using advanced high angular …