Complosome—the intracellular complement system

EE West, C Kemper - Nature Reviews Nephrology, 2023 - nature.com
The complement system is a recognized pillar of host defence against infection and noxious
self-derived antigens. Complement is traditionally known as a serum-effective system …

Anti-inflammatory potential of platinum nanozymes: mechanisms and perspectives

G Bardi, L Boselli, PP Pompa - Nanoscale, 2023 - pubs.rsc.org
Inflammation is a complex process of the body in response to pathogen infections or
dysregulated metabolism, involving the recruitment and activation of immune system …

Oral dysbiosis and autoimmunity: from local periodontal responses to an imbalanced systemic immunity. A review

LJ Suárez, H Garzón, S Arboleda… - Frontiers in …, 2020 - frontiersin.org
The current paradigm of onset and progression of periodontitis includes oral dysbiosis
directed by inflammophilic bacteria, leading to altered resolution of inflammation and lack of …

Immunological basis of the endometriosis: the complement system as a potential therapeutic target

C Agostinis, A Balduit, A Mangogna, G Zito… - Frontiers in …, 2021 - frontiersin.org
Endometriosis (EM) is a chronic disease characterized by the presence and proliferation of
functional endometrial glands and stroma outside the uterine cavity. Ovaries and pelvic …

Contribution of adaptive immunity to human COPD and experimental models of emphysema

F Kheradmand, Y Zhang, DB Corry - Physiological Reviews, 2023 - journals.physiology.org
The pathophysiology of chronic obstructive pulmonary disease (COPD) and the undisputed
role of innate immune cells in this condition have dominated the field in the basic research …

Autoimmunity in primary immunodeficiency disorders: an updated review on pathogenic and clinical implications

G Costagliola, S Cappelli, R Consolini - Journal of Clinical Medicine, 2021 - mdpi.com
During the last years, studies investigating the intriguing association between
immunodeficiency and autoimmunity led to the discovery of new monogenic disorders, the …

Microglia as therapeutic target for radiation-induced brain injury

Q Liu, Y Huang, M Duan, Q Yang, B Ren… - International journal of …, 2022 - mdpi.com
Radiation-induced brain injury (RIBI) after radiotherapy has become an increasingly
important factor affecting the prognosis of patients with head and neck tumor. With the …

Complement deficiencies and dysregulation: Pathophysiological consequences, modern analysis, and clinical management

J Schröder-Braunstein, M Kirschfink - Molecular immunology, 2019 - Elsevier
Complement defects are associated with an enhanced risk of a broad spectrum of infectious
as well as systemic or local inflammatory and thrombotic disorders. Inherited complement …

The mosaic of autoimmunity–Finally discussing in person. The 13th international congress on autoimmunity 2022 (AUTO13) Athens

N Mahroum, A Elsalti, A Alwani, I Seida, M Alrais… - Autoimmunity …, 2022 - Elsevier
While autoimmunity is a branch of medicine linked to every single organ system via direct
and indirect pathways, meeting in person to discuss autoimmunity during the 13 th …

Roles of interferon induced protein with tetratricopeptide repeats (IFIT) family in autoimmune disease

YY Wu, J Xing, XF Li, YL Yang, H Shao, J Li - Autoimmunity Reviews, 2023 - Elsevier
Interferon-induced tetrapeptide repeat (IFIT) family proteins are an important component of
the antiviral immune response. There are four known members of the human IFIT family …