Algorithmic fairness in artificial intelligence for medicine and healthcare

RJ Chen, JJ Wang, DFK Williamson, TY Chen… - Nature biomedical …, 2023 - nature.com
In healthcare, the development and deployment of insufficiently fair systems of artificial
intelligence (AI) can undermine the delivery of equitable care. Assessments of AI models …

Polygenic risk scores for cardiovascular disease: a scientific statement from the American Heart Association

JW O'Sullivan, S Raghavan, C Marquez-Luna… - Circulation, 2022 - Am Heart Assoc
Cardiovascular disease is the leading contributor to years lost due to disability or premature
death among adults. Current efforts focus on risk prediction and risk factor mitigation ‚which …

Precision medicine, AI, and the future of personalized health care

KB Johnson, WQ Wei, D Weeraratne… - Clinical and …, 2021 - Wiley Online Library
The convergence of artificial intelligence (AI) and precision medicine promises to
revolutionize health care. Precision medicine methods identify phenotypes of patients with …

The “All of Us” research program

All of Us Research Program … - New England Journal of …, 2019 - Mass Medical Soc
Knowledge gained from observational cohort studies has dramatically advanced the
prevention and treatment of diseases. Many of these cohorts, however, are small, lack …

GA4GH: International policies and standards for data sharing across genomic research and healthcare

HL Rehm, AJH Page, L Smith, JB Adams, G Alterovitz… - Cell genomics, 2021 - cell.com
Summary The Global Alliance for Genomics and Health (GA4GH) aims to accelerate
biomedical advances by enabling the responsible sharing of clinical and genomic data …

From big data to precision medicine

T Hulsen, SS Jamuar, AR Moody, JH Karnes… - Frontiers in …, 2019 - frontiersin.org
For over a decade the term “Big data” has been used to describe the rapid increase in
volume, variety and velocity of information available, not just in medical research but in …

Development and validation of a trans-ancestry polygenic risk score for type 2 diabetes in diverse populations

T Ge, MR Irvin, A Patki, V Srinivasasainagendra… - Genome Medicine, 2022 - Springer
Abstract Background Type 2 diabetes (T2D) is a worldwide scourge caused by both genetic
and environmental risk factors that disproportionately afflicts communities of color …

[HTML][HTML] Opportunities and challenges in developing risk prediction models with electronic health records data: a systematic review

BA Goldstein, AM Navar, MJ Pencina… - Journal of the …, 2017 - ncbi.nlm.nih.gov
Objective: Electronic health records (EHRs) are an increasingly common data source for
clinical risk prediction, presenting both unique analytic opportunities and challenges. We …

AI in health: state of the art, challenges, and future directions

F Wang, A Preininger - Yearbook of medical informatics, 2019 - thieme-connect.com
Introduction: Artificial intelligence (AI) technologies continue to attract interest from a broad
range of disciplines in recent years, including health. The increase in computer hardware …

A framework for enhancing ethical genomic research with Indigenous communities

KG Claw, MZ Anderson, RL Begay, KS Tsosie… - Nature …, 2018 - nature.com
Integration of genomic technology into healthcare settings establishes new capabilities to
predict disease susceptibility and optimize treatment regimes. Yet, Indigenous peoples …