Advances in anti hepatic fibrotic therapy with Traditional Chinese Medicine herbal formula

H Li - Journal of Ethnopharmacology, 2020 - Elsevier
Ethnopharmacological relevance The process of liver fibrogenesis includes a number of
common and etiology-dependent or independent mechanisms and events. Up to now, there …

[HTML][HTML] Liver fibrosis resolution: from molecular mechanisms to therapeutic opportunities

Q Pei, Q Yi, L Tang - International Journal of Molecular Sciences, 2023 - mdpi.com
The liver is a critical system for metabolism in human beings, which plays an essential role
in an abundance of physiological processes and is vulnerable to endogenous or exogenous …

Isolation, purification, and physicochemical characterization of Polygonatum polysaccharide and its protective effect against CCl4-induced liver injury via Nrf2 and NF …

G Yuan, Y Wang, H Niu, Y Ma, J Song - International Journal of Biological …, 2024 - Elsevier
This study aimed to provide scientific evidence that Polygonatum polysaccharide can be
developed as a dietary supplement and medication for treating liver injuries. A water-soluble …

The phytochemistry and pharmacology of three Rheum species: A comprehensive review with future perspectives

X Yang, L Dai, F Yan, Y Ma, X Guo, J Jenis, Y Wang… - Phytomedicine, 2024 - Elsevier
Background Rheum palmatum, R. tanguticum, and R. officinale, integral species of the
genus Rheum, are widely used across global temperate and subtropical regions. These …

Jiawei Taohe Chengqi decoction inhibition of the notch signal pathway affects macrophage reprogramming to inhibit HSCs activation for the treatment of hepatic …

C Shao, H Xu, X Sun, Y Pan, X Liang, J Huang… - Journal of …, 2024 - Elsevier
Abstract Ethnopharmacological relevance Jiawei Taohe Chengqi Tang (JTCD) is a modified
formulation of Traditional Chinese Medicine (TCM) known as Taohe Chengqi Decoction …

[HTML][HTML] Salvianolic acid B inhibits autophagy and activation of hepatic stellate cells induced by TGF-β1 by downregulating the MAPK pathway

N Jiang, J Zhang, J Ping, L Xu - Frontiers in Pharmacology, 2022 - frontiersin.org
In liver fibrosis, transforming growth factor-β1 (TGF-β1) can stimulate autophagy and
activation of hepatic stellate cells (HSCs). Autophagy, playing a crucial role in HSCs …

[HTML][HTML] A comprehensive review of emodin in fibrosis treatment

X Jia, H Liu, X Zhang, Y Shao - Fitoterapia, 2023 - Elsevier
Emodin is the main pharmacodynamic components of rhubarb, with significant
pharmacological effects and clinical efficacy. Emodin has a variety of therapy effects, such …

[HTML][HTML] Integrated network analysis and metabolomics reveal the molecular mechanism of Yinchen Sini decoction in CCl4-induced acute liver injury

W Zheng, C Shi, Y Meng, J Peng, Y Zhou… - Frontiers in …, 2023 - frontiersin.org
Objective: Yinchen Sini decoction (YCSND), a traditional Chinese medicine (TCM) formula,
plays a crucial role in the treatment of liver disease. However, the bioactive constituents and …

[HTML][HTML] Advances in the study of emodin: an update on pharmacological properties and mechanistic basis

Q Zheng, S Li, X Li, R Liu - Chinese Medicine, 2021 - Springer
Abstract Rhei Radix et Rhizoma, also known as rhubarb or Da Huang, has been widely
used as a spice and as traditional herbal medicine for centuries, and is currently marketed in …

[HTML][HTML] Traditional Chinese medicine, liver fibrosis, intestinal flora: is there any connection?—a narrative review

YT Liu, SL Qi, KW Sun - Annals of Palliative Medicine, 2021 - apm.amegroups.org
This paper aims to analyze how intestinal flora regulates liver fibrosis pathogenesis and to
evaluate the regulatory effect of traditional Chinese medicine (TCM) on the intestinal flora …