Molecular mechanisms of anticancer effect of rutin

A Imani, N Maleki, S Bohlouli… - Phytotherapy …, 2021 - Wiley Online Library
Because of the extensive biological functions of natural substances such as bioflavonoids,
and their high safety and low costs, they could have high priority application in the health …

[HTML][HTML] Targeting multiple signaling pathways in cancer: The rutin therapeutic approach

Z Nouri, S Fakhri, K Nouri, CE Wallace, MH Farzaei… - Cancers, 2020 - mdpi.com
Multiple dysregulated signaling pathways are implicated in the pathogenesis of cancer. The
conventional therapies used in cancer prevention/treatment suffer from low efficacy …

The anticancer potential of the dietary polyphenol rutin: Current status, challenges, and perspectives

AK Farha, RY Gan, HB Li, DT Wu… - Critical Reviews in …, 2022 - Taylor & Francis
Rutin is one of the most common dietary polyphenols found in vegetables, fruits, and other
plants. It is metabolized by the mammalian gut microbiota and absorbed from the intestines …

Flavonoids: Food associations, therapeutic mechanisms, metabolism and nanoformulations

N Kaushal, M Singh, RS Sangwan - Food research international, 2022 - Elsevier
Flavonoids possess an impressive therapeutic potential, thereby imparting them a
nutraceutical character. As it becomes increasingly common to consume foods associated …

[HTML][HTML] Rutin-loaded solid lipid nanoparticles: characterization and in vitro evaluation

F De Gaetano, MC Cristiano, V Venuti, V Crupi… - Molecules, 2021 - mdpi.com
This study was aimed at preparing and characterizing solid lipid nanoparticles loading rutin
(RT-SLNs) for the treatment of oxidative stress-induced diseases. Phospholipon 80H® as a …

Evaluation of the cytotoxic effect of rutin prenanoemulsion in lung and colon cancer cell lines

TT Hoai, PT Yen, TTB Dao, LH Long… - Journal of …, 2020 - Wiley Online Library
In this work, prenanoemulsion of rutin was prepared using PEG and Tween as emulsifiers
via homogenization and evaporation techniques. The particle size of rutin was investigated …

Green synthesis of silver nanocomposites of Nigella sativa seeds extract for hepatocellular carcinoma

A Usmani, A Mishra, A Jafri, M Arshad… - Current …, 2019 - ingentaconnect.com
Background: Silver nanoparticles play a significant role in bioavailability and refining the
compatibility of natural drugs in the treatment of various chronic diseases including different …

[HTML][HTML] A mini-review of reactive oxygen species in urological cancer: correlation with NADPH oxidases, angiogenesis, and apoptosis

Y Miyata, T Matsuo, Y Sagara, K Ohba… - International journal of …, 2017 - mdpi.com
Oxidative stress refers to elevated reactive oxygen species (ROS) levels, and NADPH
oxidases (NOXs), which are one of the most important sources of ROS. Oxidative stress …

[HTML][HTML] Flavonoid-based nanomedicines to target tumor microenvironment

WH Talib, A Abuawad, S Thiab, A Alshweiat… - OpenNano, 2022 - Elsevier
Cancer cells arise and grow in tumor microenvironment which consists of stromal cells and
extracellular matrix. The dynamic interaction between cancer cells and different components …

[HTML][HTML] Inhibitory potential of rutin and rutin nano-crystals against Helicobacter pylori, colon cancer, hemolysis and Butyrylcholinesterase in vitro and in silico

H Qanash, AMH Al-Rajhi, MN Almashjary… - Applied Biological …, 2023 - Springer
Despite the vital activity of many compounds, they lack that effectiveness due to their low
solubility in water. Unfortunately, for this reason, rutin often leads to low tissue permeability …