[HTML][HTML] Myocarditis and inflammatory cardiomyopathy: current evidence and future directions

C Tschöpe, E Ammirati, B Bozkurt… - Nature Reviews …, 2021 - nature.com
Inflammatory cardiomyopathy, characterized by inflammatory cell infiltration into the
myocardium and a high risk of deteriorating cardiac function, has a heterogeneous …

Inflammation and fibrosis in murine models of heart failure

L Bacmeister, M Schwarzl, S Warnke, B Stoffers… - Basic research in …, 2019 - Springer
Heart failure is a consequence of various cardiovascular diseases and associated with poor
prognosis. Despite progress in the treatment of heart failure in the past decades, prevalence …

Post-Stroke Cardiovascular Complications and Neurogenic Cardiac Injury: JACC State-of-the-Art Review

LA Sposato, MJ Hilz, S Aspberg, SB Murthy… - Journal of the american …, 2020 - jacc.org
Over 1.5 million deaths worldwide are caused by neurocardiogenic syndromes.
Furthermore, the consequences of deleterious brain-heart interactions are not limited to fatal …

Inflammation–cause or consequence of heart failure or both?

S Van Linthout, C Tschöpe - Current heart failure reports, 2017 - Springer
Abstract Purpose of Review With the intention to summarize the currently available evidence
on the pathophysiological relevance of inflammation in heart failure, this review addresses …

Piezo1 channels as force sensors in mechanical force-related chronic inflammation

H Liu, J Hu, Q Zheng, X Feng, F Zhan, X Wang… - Frontiers in …, 2022 - frontiersin.org
Mechanical damage is one of the predisposing factors of inflammation, and it runs through
the entire inflammatory pathological process. Repeated or persistent damaging mechanical …

Management of myocarditis-related cardiomyopathy in adults

C Tschöpe, LT Cooper, G Torre-Amione… - Circulation …, 2019 - Am Heart Assoc
Myocarditis is generally a mild and self-limited consequence of systemic infection of
cardiotropic viruses. However, patients can develop a temporary or permanent impairment …

From inflammation to fibrosis—molecular and cellular mechanisms of myocardial tissue remodelling and perspectives on differential treatment opportunities

N Suthahar, WC Meijers, HHW Silljé… - Current heart failure …, 2017 - Springer
Abstract Purpose of Review In this review, we highlight the most important cellular and
molecular mechanisms that contribute to cardiac inflammation and fibrosis. We also discuss …

Complexity of TNF-α signaling in heart disease

F Rolski, P Błyszczuk - Journal of clinical medicine, 2020 - mdpi.com
Heart disease is a leading cause of death with unmet clinical needs for targeted treatment
options. Tumor necrosis factor alpha (TNF-α) represents a master pro-inflammatory cytokine …

Cardiac fibroblasts and mechanosensation in heart development, health and disease

M Pesce, GN Duda, G Forte, H Girao, A Raya… - Nature Reviews …, 2023 - nature.com
The term 'mechanosensation'describes the capacity of cells to translate mechanical stimuli
into the coordinated regulation of intracellular signals, cellular function, gene expression …

Atrial remodeling, fibrosis, and atrial fibrillation

J Jalife, K Kaur - Trends in cardiovascular medicine, 2015 - Elsevier
The fundamental mechanisms governing the perpetuation of atrial fibrillation (AF), the most
common arrhythmia seen in clinical practice, are poorly understood, which explains in part …