Prolonged microgravity exposure during long-duration spaceflight (LDSF) produces unusual
physiologic and pathologic neuro-ophthalmic findings in astronauts. These microgravity …

The field of human space travel is in the midst of a dramatic revolution. Upcoming missions
are looking to push the boundaries of space travel, with plans to travel for longer distances …

Background There is limited information regarding the effects of spaceflight on the
anatomical configuration of the brain and on cerebrospinal fluid (CSF) spaces. Methods We …

Long-duration spaceflight induces changes to the brain and cerebrospinal fluid
compartments and visual acuity problems known as spaceflight-associated neuro-ocular …

During spaceflight, the central nervous system (CNS) is exposed to a complex array of
environmental stressors. However, the effects of long-duration spaceflight on the CNS and …

Space travel presents a number of environmental challenges to the central nervous system,
including changes in gravitational acceleration that alter the terrestrial synergies between …

Background Astronauts on long-duration spaceflight missions may develop changes in
ocular structure and function, which can persist for years after the return to normal gravity …

Importance Spaceflight results in transient balance declines and brain morphologic
changes; to our knowledge, the effect on brain white matter as measured by diffusion …

As human space exploration advances to establish a permanent presence beyond the Low
Earth Orbit (LEO) with NASA's Artemis mission, researchers are striving to understand and …

Weightlessness in space induces a fluid shift from the dependent to the cephalad parts of
the body leading to distension of the cardiac chambers and an accumulation of blood in the …