The multidimensional mechanisms of long noncoding RNA function
A major shift in our understanding of genome regulation has emerged recently. It is now
apparent that the majority of cellular transcripts do not code for proteins, and many of them …
apparent that the majority of cellular transcripts do not code for proteins, and many of them …
The emerging role of lncRNAs in cancer
M Huarte - Nature medicine, 2015 - nature.com
It is increasingly evident that many of the genomic mutations in cancer reside inside regions
that do not encode proteins. However, these regions are often transcribed into long …
that do not encode proteins. However, these regions are often transcribed into long …
LncRNA LINC00969 promotes acquired gefitinib resistance by epigenetically suppressing of NLRP3 at transcriptional and posttranscriptional levels to inhibit …
J Dai, T Qu, D Yin, Y Cui, C Zhang, E Zhang… - Cell death & …, 2023 - nature.com
Epidermal growth factor receptor-tyrosine kinase inhibitor (EGFR-TKI) treatment prolongs
the survival of lung cancer patients harbouring activating EGFR mutations. However …
the survival of lung cancer patients harbouring activating EGFR mutations. However …
HOTAIR: an oncogenic long non-coding RNA in human cancer
Q Tang, SS Hann - Cellular Physiology and Biochemistry, 2018 - karger.com
Abstract Long non-coding RNAs (LncRNAs) represent a novel class of noncoding RNAs that
are longer than 200 nucleotides without protein-coding potential and function as novel …
are longer than 200 nucleotides without protein-coding potential and function as novel …
H3K27 acetylation activated-long non-coding RNA CCAT1 affects cell proliferation and migration by regulating SPRY4 and HOXB13 expression in esophageal …
E Zhang, L Han, D Yin, X He, L Hong, X Si… - Nucleic acids …, 2017 - academic.oup.com
Recently, long non-coding RNAs (lncRNAs) have been shown to have important regulatory
roles in human cancer biology. In our study, we found that lncRNA CCAT1, whose …
roles in human cancer biology. In our study, we found that lncRNA CCAT1, whose …
The functional role of long non-coding RNAs and epigenetics
J Cao - Biological procedures online, 2014 - Springer
Long non-coding RNAs (lncRNAs) are non-protein coding transcripts longer than 200
nucleotides. The post-transcriptional regulation is influenced by these lncRNAs by …
nucleotides. The post-transcriptional regulation is influenced by these lncRNAs by …
HOTAIR LncRNA: a novel oncogenic propellant in human cancer
T Rajagopal, S Talluri, RL Akshaya, NR Dunna - Clinica chimica acta, 2020 - Elsevier
Long non-coding RNAs (lncRNAs) are an important novel class of non-coding RNAs having
lengths of 200 nucleotides and low expression. The HOX Transcript Antisense Intergenic …
lengths of 200 nucleotides and low expression. The HOX Transcript Antisense Intergenic …
Insights into biological role of LncRNAs in epithelial-mesenchymal transition
Long non-coding RNAs (lncRNAs) are versatile regulators of gene expression and play
crucial roles in diverse biological processes. Epithelial-mesenchymal transition (EMT) is a …
crucial roles in diverse biological processes. Epithelial-mesenchymal transition (EMT) is a …
Long noncoding RNA dysregulation in ischemic heart failure
S Greco, G Zaccagnini, A Perfetti, P Fuschi… - Journal of translational …, 2016 - Springer
Abstract Background Long noncoding RNAs (lncRNAs) are non-protein coding transcripts
regulating a variety of physiological and pathological functions. However, their implication in …
regulating a variety of physiological and pathological functions. However, their implication in …
The specificity of long noncoding RNA expression
Over the last decade, long noncoding RNAs (lncRNAs) have emerged as a fundamental
molecular class whose members play pivotal roles in the regulation of the genome. The …
molecular class whose members play pivotal roles in the regulation of the genome. The …