Adult chronic rhinosinusitis

C Bachert, B Marple, RJ Schlosser, C Hopkins… - Nature reviews Disease …, 2020 - nature.com
Chronic rhinosinusitis (CRS) occurs in> 10% of the adult population in Europe and the USA
and can be differentiated into CRS without nasal polyps and CRS with nasal polyps …

[PDF][PDF] EPOS/EUFOREA update on indication and evaluation of Biologics in Chronic Rhinosinusitis with Nasal Polyps 2023

WJ Fokkens, AS Viskens, V Backer, D Conti… - Rhinology, 2023 - sioechcf.it
Severe chronic rhinosinusitis with nasal polyps (CRSwNP) is a debilitating disease with a
significant impact on the quality of life (QoL). It is typically characterized by a type 2 …

EUFOREA expert board meeting on uncontrolled severe chronic rhinosinusitis with nasal polyps (CRSwNP) and biologics: definitions and management

C Bachert, JK Han, M Wagenmann… - Journal of Allergy and …, 2021 - Elsevier
Uncontrolled severe chronic rhinosinusitis with nasal polyps (CRSwNP) is the most
bothersome phenotype of chronic rhinosinusitis; it is typically characterized by a type 2 …

[HTML][HTML] How to manage recurrences after surgery in CRSwNP patients in the biologic era: a narrative review

E De Corso, S Settimi, C Montuori… - Acta …, 2023 - ncbi.nlm.nih.gov
Objective This narrative review analyses factors affecting recurrence of Chronic
rhinosinusitis with nasal polyps (CRSwNP) after surgery, such as type, extension and …

Prognostic factors for polyp recurrence in chronic rhinosinusitis with nasal polyps

J Bai, JH Huang, CPE Price, JM Schauer… - Journal of Allergy and …, 2022 - Elsevier
Background Chronic rhinosinusitis with nasal polyps is frequently managed with endoscopic
sinus surgery (ESS). Prior studies describe individual clinical variables and eosinophil …

[HTML][HTML] Mepolizumab for chronic rhinosinusitis with nasal polyps: treatment efficacy by comorbidity and blood eosinophil count

C Bachert, AR Sousa, JK Han, RJ Schlosser… - Journal of Allergy and …, 2022 - Elsevier
Background In the Phase III SYNAPSE study, mepolizumab reduced nasal polyp (NP) size
and nasal obstruction in chronic rhinosinusitis with NP (CRSwNP). Objective To assess the …

Efficacy of dupilumab in patients with a history of prior sinus surgery for chronic rhinosinusitis with nasal polyps

C Hopkins, M Wagenmann, C Bachert… - International forum of …, 2021 - Wiley Online Library
Background Chronic rhinosinusitis with nasal polyps (CRSwNP) is a type 2 inflammatory
disease treated with sinus surgery when refractory to medical intervention. However …

Cost utility analysis of dupilumab versus endoscopic sinus surgery for chronic rhinosinusitis with nasal polyps

GA Scangas, AW Wu, JY Ting, R Metson… - The …, 2021 - Wiley Online Library
Objective Both endoscopic sinus surgery (ESS) and biologic therapies have shown
effectiveness for medically‐refractory chronic rhinosinusitis with nasal polyps (CRSwNP) …

A comparative analysis of endoscopic sinus surgery versus biologics for treatment of chronic rhinosinusitis with nasal polyposis

A Miglani, ZM Soler, TL Smith, JC Mace… - International forum of …, 2023 - Wiley Online Library
Background Comparative effectiveness research between endoscopic sinus surgery (ESS)
and biologic therapy for severe chronic rhinosinusitis with nasal polyposis (CRSwNP) is a …

The role of biologics in chronic rhinosinusitis with nasal polyps

GB Patel, AT Peters - Ear, Nose & Throat Journal, 2021 - journals.sagepub.com
Biologic therapy is a new treatment option for patients with chronic rhinosinusitis with nasal
polyps (CRSwNP). Currently, the only biologic with Food and Drug Administration–approval …