It is well established that adipose tissue, apart from its energy storage function, acts as an
endocrine organ that produces and secretes a number of bioactive substances, including …

Objectives The cytokine oncostatin M (OSM) is implicated in the pathology of SSc. Inhibiting
OSM signalling using GSK2330811 (an anti-OSM monoclonal antibody) in patients with SSc …

Background: Oncostatin M, a novel adipokine, plays a role in oogenesis, lipogenesis, and
inflammation and may contribute to polycystic ovary syndrome pathogenesis and related …

Oncostatin M (OSM) is a member of the glycoprotein 130 cytokine family that is involved in
chronic inflammation and increased in adipose tissue under obesity and insulin resistance …

Objectives This study was designed to clarify the effects of ghrelin on myocardial and aortic
tissues in insulin-resistant rats. Methods Sprague-Dawley rats were divided into the …

Despite its high prevalence, our understanding of the pathophysiology of polycystic ovary
syndrome (PCOS) is lacking. Consequently, the way we diagnose and manage this common …

Abstract Objective: To compare the Oncostatin M (OSM) concentrations in tissues of patients
with chronic periodontitis with and without diabetes. Material and Methods: Sixty-four …

ABSTRACT Background: Oncostatin M (OSM), a 28 kDa gp130 pleiotropic cytokine
belonging to the Interleukin-6 family is mainly produced by neutrophils, activated T cells …