Alcoholic liver disease

HK Seitz, R Bataller, H Cortez-Pinto, B Gao… - Nature reviews Disease …, 2018 - nature.com
Alcoholic liver disease (ALD) is the most prevalent type of chronic liver disease worldwide.
ALD can progress from alcoholic fatty liver (AFL) to alcoholic steatohepatitis (ASH), which is …

Lipids and oxidative stress associated with ethanol‐induced neurological damage

JA Hernández, RC López-Sánchez… - Oxidative medicine …, 2016 - Wiley Online Library
The excessive intake of alcohol is a serious public health problem, especially given the
severe damage provoked by chronic or prenatal exposure to alcohol that affects many …

Gender differences in pharmacokinetics of alcohol

E Baraona, CS Abittan, K Dohmen… - Alcoholism: Clinical …, 2001 - Wiley Online Library
Background: The enhanced vulnerability of women to develop alcohol‐related diseases
may be due to their higher blood alcohol levels after drinking, but the mechanism for this …

[图书][B] A primer of drug action: A concise nontechnical guide to the actions, uses, and side effects of psychoactive drugs, revised and updated

RM Julien - 2013 - books.google.com
Since 1975, Robert Julien's A Primer of Drug Action has been the definitive guide to the
effects of psychoactive drugs on the brain and on behavior. Now fully updated, this popular …

[图书][B] Hepatology Principles and Practice: History· Morphology Biochemistry· Diagnostics Clinic· Therapy

E Kuntz - 2006 - Springer
Metabolic processes utilize a variety of differing and contrasting biochemical routes to
enable synthesis of degradation and activation or deactivation of substances; in addition …

Role of variability in explaining ethanol pharmacokinetics: research and forensic applications

Å Norberg, AW Jones, RG Hahn… - Clinical pharmacokinetics, 2003 - Springer
Variability in the rate and extent of absorption, distribution and elimination of ethanol has
important ramifications in clinical and legal medicine. The speed of absorption of ethanol …

Ethanol metabolism and its effects on the intestinal epithelial barrier

EE Elamin, AA Masclee, J Dekker… - Nutrition …, 2013 - academic.oup.com
Ethanol is widely consumed and is associated with an increasing global health burden.
Several reviews have addressed the effects of ethanol and its oxidative metabolite …

Research advances in ethanol metabolism

VA Ramchandani, WF Bosron, TK Li - Pathologie Biologie, 2001 - Elsevier
The pharmacokinetics of alcohol determines the time course of alcohol concentration in
blood after the ingestion of an alcoholic beverage and the degree of exposure of organs to …

Age, alcohol metabolism and liver disease

P Meier, HK Seitz - Current Opinion in Clinical Nutrition & …, 2008 - journals.lww.com
Over recent decades alcohol consumption has increased among those who are older than
65 years. Alcohol is more toxic in the ageing organism because of changes in its …

Alcohol, its absorption, distribution, metabolism, and excretion in the body and pharmacokinetic calculations

AW Jones - Wiley Interdisciplinary Reviews: Forensic Science, 2019 - Wiley Online Library
The ethanol contained in alcoholic beverages is rapidly absorbed from the gastrointestinal
tract and the maximum blood‐alcohol concentration (BAC) is usually reached between 10 …