pH-responsive polymeric nanomaterials for the treatment of oral biofilm infections
Bacterial and fungal pathogens forming oral biofilms present significant public health
challenges due to the failure of antimicrobial drugs. The ability of biofilms to lower pH levels …
challenges due to the failure of antimicrobial drugs. The ability of biofilms to lower pH levels …
Glycosylation and lipidation strategies: Approaches for improving antimicrobial peptide efficacy
R Bellavita, S Braccia, S Galdiero, A Falanga - Pharmaceuticals, 2023 - mdpi.com
Antimicrobial peptides (AMPs) have recently gained attention as a viable solution for
combatting antibiotic resistance due to their numerous advantages, including their broad …
combatting antibiotic resistance due to their numerous advantages, including their broad …
[HTML][HTML] Plastic pollution and fungal, protozoan, and helminth pathogens–A neglected environmental and public health issue?
Plastic waste is ubiquitous in the environment and can become colonised by distinct
microbial biofilm communities, known collectively as the 'plastisphere.'The plastisphere can …
microbial biofilm communities, known collectively as the 'plastisphere.'The plastisphere can …
Effect of Myrtenol and Its Synergistic Interactions with Antimicrobial Drugs in the Inhibition of Single and Mixed Biofilms of Candida auris and Klebsiella pneumoniae
A Maione, A La Pietra, E de Alteriis, A Mileo… - Microorganisms, 2022 - mdpi.com
The increased incidence of mixed infections requires that the scientific community develop
novel antimicrobial molecules. Essential oils and their bioactive pure compounds have been …
novel antimicrobial molecules. Essential oils and their bioactive pure compounds have been …
Unveiling the mechanism of action of acylated temporin L analogues against multidrug-resistant Candida albicans
R Bellavita, A Falanga, F Merlino… - Journal of Enzyme …, 2023 - Taylor & Francis
The increasing resistance of fungi to conventional antifungal drugs has prompted worldwide
the search for new compounds. In this work, we investigated the antifungal properties of …
the search for new compounds. In this work, we investigated the antifungal properties of …
Mixed fungal biofilms: From mycobiota to devices, a new challenge on clinical practice
Most current protocols for the diagnosis of fungal infections are based on culture-dependent
methods that allow the evaluation of fungal morphology and the identification of the etiologic …
methods that allow the evaluation of fungal morphology and the identification of the etiologic …
Synthetic Amphipathic β-Sheet Temporin-Derived Peptide with Dual Antibacterial and Anti-Inflammatory Activities
R Bellavita, E Buommino, B Casciaro, F Merlino… - Antibiotics, 2022 - mdpi.com
Temporin family is one of the largest among antimicrobial peptides (AMPs), which act mainly
by penetrating and disrupting the bacterial membranes. To further understand the …
by penetrating and disrupting the bacterial membranes. To further understand the …
Myxinidin-derived peptide against biofilms caused by cystic fibrosis emerging pathogens
R Bellavita, A Maione, S Braccia, M Sinoca… - International Journal of …, 2023 - mdpi.com
Chronic lung infections in cystic fibrosis (CF) patients are triggered by multidrug-resistant
bacteria such as Pseudomonas aeruginosa, Achromobacter xylosoxidans, and …
bacteria such as Pseudomonas aeruginosa, Achromobacter xylosoxidans, and …
Effect of Escin Alone or in Combination with Antifungal Agents on Resistant Candida glabrata Biofilms: Mechanisms of Action
A Maione, M Imparato, M Galdiero, E Alteriis, A Feola… - Antibiotics, 2023 - mdpi.com
Nowadays, the increase in antimicrobial-resistant fungi (AMR) is certainly a major health
concern, and the development of alternative therapeutic strategies has become crucial …
concern, and the development of alternative therapeutic strategies has become crucial …
Strategic Single-Residue Substitution in the Antimicrobial Peptide Esc(1–21) Confers Activity against Staphylococcus aureus, Including Drug-Resistant and Biofilm …
MR Loffredo, B Casciaro, R Bellavita… - ACS Infectious …, 2024 - ACS Publications
Staphylococcus aureus, a bacterium resistant to multiple drugs, is a significant cause of
illness and death worldwide. Antimicrobial peptides (AMPs) provide an excellent potential …
illness and death worldwide. Antimicrobial peptides (AMPs) provide an excellent potential …