Neurovascular coupling in humans: physiology, methodological advances and clinical implications

AA Phillips, FHN Chan, MMZ Zheng… - Journal of Cerebral …, 2016 - journals.sagepub.com
Neurovascular coupling reflects the close temporal and regional linkage between neural
activity and cerebral blood flow. Although providing mechanistic insight, our understanding …

Hormonal and metabolic changes of aging and the influence of lifestyle modifications

MW Pataky, WF Young, KS Nair - Mayo Clinic Proceedings, 2021 - Elsevier
Increased life expectancy combined with the aging baby boomer generation has resulted in
an unprecedented global expansion of the elderly population. The growing population of …

The effect of cycling on cognitive function and well-being in older adults

LA Leyland, B Spencer, N Beale, T Jones… - PloS one, 2019 - journals.plos.org
It has been demonstrated that, on their own, both exercise and stimulation from the
environment can improve cognitive function and well-being in older adults. The combined …

Safety and prognostic utility of provocative exercise testing in acutely concussed adolescents: a randomized trial

JJ Leddy, AL Hinds, J Miecznikowski… - Clinical journal of …, 2018 - journals.lww.com
Objective: To evaluate (1) systematic assessment of exercise tolerance in adolescents
shortly after sport-related concussion (SRC) and (2) the prognostic utility of such …

Active rehabilitation of concussion and post-concussion syndrome

JJ Leddy, JG Baker, B Willer - Physical Medicine and …, 2016 - pmr.theclinics.com
Rest has been the mainstay of the treatment for concussion. 1 Research based on animal
physiological concussion studies suggests that the concussed human brain is in a …

Exercise intervention associated with cognitive improvement in Alzheimer's disease

MY Cui, Y Lin, JY Sheng, X Zhang, RJ Cui - Neural plasticity, 2018 - Wiley Online Library
Alzheimer's disease (AD) is a progressive neurodegenerative disease with the syndrome of
cognitive and functional decline. Pharmacotherapy has always been in a dominant position …

The role of controlled exercise in concussion management

J Leddy, A Hinds, D Sirica, B Willer - Pm&r, 2016 - Elsevier
Concussion affects the autonomic nervous system and its control of cerebral blood flow,
which may be why uncontrolled activity can exacerbate symptoms after concussion …

High-intensity interval exercise and cerebrovascular health: curiosity, cause, and consequence

SJE Lucas, JD Cotter, P Brassard… - Journal of Cerebral …, 2015 - journals.sagepub.com
Exercise is a uniquely effective and pluripotent medicine against several noncommunicable
diseases of westernised lifestyles, including protection against neurodegenerative …

A preliminary study of the effect of early aerobic exercise treatment for sport-related concussion in males

JJ Leddy, MN Haider, AL Hinds… - Clinical journal of sport …, 2019 - journals.lww.com
Objective: To study the effect of early prescribed aerobic exercise versus relative rest on rate
of recovery in male adolescents acutely after sport-related concussion (SRC). Design: Quasi …

Acute effects of exercise engagement on neurocognitive function: a systematic review and meta-analysis on P3 amplitude and latency

SC Kao, FT Chen, D Moreau, ES Drollette… - … Review of Sport and …, 2022 - Taylor & Francis
Although the acute effect of exercise on behavioral cognitive performance is well-
documented in the exercise psychology field, a comprehensive evaluation on neuroelectric …