Reward circuitry dysfunction in psychiatric and neurodevelopmental disorders and genetic syndromes: animal models and clinical findings
This review summarizes evidence of dysregulated reward circuitry function in a range of
neurodevelopmental and psychiatric disorders and genetic syndromes. First, the …
neurodevelopmental and psychiatric disorders and genetic syndromes. First, the …
Eating beyond metabolic need: how environmental cues influence feeding behavior
AW Johnson - Trends in neurosciences, 2013 - cell.com
Animals use current, past, and projected future states of the organism and the world in a
finely tuned system to control ingestion. They must not only deal effectively with current …
finely tuned system to control ingestion. They must not only deal effectively with current …
Nutritional phases in Prader–Willi syndrome
JL Miller, CH Lynn, DC Driscoll… - American journal of …, 2011 - Wiley Online Library
Prader–Willi syndrome (PWS) is a complex neurobehavioral condition which has been
classically described as having two nutritional stages: poor feeding, frequently with failure to …
classically described as having two nutritional stages: poor feeding, frequently with failure to …
Development of the eating behaviour in Prader–Willi Syndrome: advances in our understanding
CJ McAllister, JE Whittington, AJ Holland - International Journal of …, 2011 - nature.com
Abstract Prader–Willi Syndrome (PWS) is a genetically determined neurodevelopmental
disorder associated with mild to moderate intellectual disability, growth and sex-hormone …
disorder associated with mild to moderate intellectual disability, growth and sex-hormone …
Ghrelin and eating behavior: evidence and insights from genetically-modified mouse models
Ghrelin is an octanoylated peptide hormone, produced by endocrine cells of the stomach,
which acts in the brain to increase food intake and body weight. Our understanding of the …
which acts in the brain to increase food intake and body weight. Our understanding of the …
A review of chemosensory perceptions, food preferences and food-related behaviours in subjects with Prader–Willi Syndrome
LM Michel, AM Haqq, WV Wismer - Appetite, 2016 - Elsevier
Hyperphagia and obsessive preoccupation with food are hallmark characteristics of Prader–
Willi Syndrome (PWS). Although hyperphagia in PWS is linked to hypothalamic dysfunction …
Willi Syndrome (PWS). Although hyperphagia in PWS is linked to hypothalamic dysfunction …
Biased signaling: A viable strategy to drug ghrelin receptors for the treatment of obesity
Obesity is a global burden and a chronic ailment with damaging overall health effects.
Ghrelin, an octanoylated 28 amino acid peptide hormone, is secreted from the oxyntic …
Ghrelin, an octanoylated 28 amino acid peptide hormone, is secreted from the oxyntic …
Appetitive motivational deficits in individuals with Parkinson's disease
Parkinson's disease is known for its effects on sensorimotor coordination caused by
degeneration of the nigrostriatal dopamine pathway. Dopamine‐innervated areas of the …
degeneration of the nigrostriatal dopamine pathway. Dopamine‐innervated areas of the …
Behavioural and cognitive profiles of mouse models for Prader–Willi syndrome
D Relkovic, AR Isles - Brain research bulletin, 2013 - Elsevier
Prader–Willi syndrome (PWS) is a neurodevelopmental disorder with aspects of psychiatric
illness caused by genetic mutations at chromosome 15q11-q13. In addition to causing PWS …
illness caused by genetic mutations at chromosome 15q11-q13. In addition to causing PWS …
Enhanced appetitive learning and reversal learning in a mouse model for Prader-Willi syndrome.
D Relkovic, T Humby, JJ Hagan… - Behavioral …, 2012 - psycnet.apa.org
Prader-Willi syndrome (PWS) is caused by lack of paternally derived gene expression from
the imprinted gene cluster on human chromosome 15q11-q13. PWS is characterized by …
the imprinted gene cluster on human chromosome 15q11-q13. PWS is characterized by …