Organoids are three‐dimensional (3D) miniaturized versions of organs or tissues that are
derived from cells with stem potential and can self‐organize and differentiate into 3D cell …

With the rapid development of population ageing, bone-related diseases seriously affecting
the life of the elderly. Over the past few years, organoids, cell clusters with specific functions …

Retinal diseases are a rising concern as major causes of blindness in an aging society;
therapeutic options are limited, and the precise pathogenesis of these diseases remains …

In recent decades, microphysiological constructs and systems (MPCs and MPSs) have
undergone significant development, ranging from self‐organized organoids to high …

The remarkable advancements related to cerebral organoids have provided unprecedented
opportunities to model human brain development and diseases. However, despite their …

Understanding the signals from the physical microenvironment is critical for deciphering the
processes of neurogenesis and neurodevelopment. The discovery of how surrounding …

Several retinal degenerations affect the human central retina, which is primarily comprised
of cones and is essential for high acuity and color vision. Transplanting cone photoreceptors …

Retinal organoids are three-dimensional (3D) structures derived from human pluripotent
stem cells (hPSCs) that mimic the retina's spatial and temporal differentiation, making them …

Retinitis pigmentosa (RP), a heterogenous group of inherited retinal disorder, causes slow
progressive vision loss with no effective treatments available. Mutations in the rhodopsin …

Diseases leading to retinal cell loss can cause severe visual impairment and blindness. The
lack of effective therapies to address retinal cell loss and the absence of intrinsic …