Exosome-based smart drug delivery tool for cancer theranostics

R Kar, R Dhar, S Mukherjee, S Nag… - ACS biomaterials …, 2023 - ACS Publications
Exosomes are the phospholipid-membrane-bound subpopulation of extracellular vesicles
derived from the plasma membrane. The main activity of exosomes is cellular …

[HTML][HTML] Functionalized liposomes for targeted breast cancer drug delivery

J Nel, K Elkhoury, É Velot, A Bianchi, S Acherar… - Bioactive materials, 2023 - Elsevier
Despite the exceptional progress in breast cancer pathogenesis, prognosis, diagnosis, and
treatment strategies, it remains a prominent cause of female mortality worldwide …

Isolation and characterization of exosomes for cancer research

L Zhu, HT Sun, S Wang, SL Huang, Y Zheng… - Journal of hematology & …, 2020 - Springer
Exosomes are a subset of extracellular vesicles that carry specific combinations of proteins,
nucleic acids, metabolites, and lipids. Mounting evidence suggests that exosomes …

Biopolymer-liposome hybrid systems for controlled delivery of bioactive compounds: Recent advances

C Tan, J Wang, B Sun - Biotechnology Advances, 2021 - Elsevier
Conventional liposomes still face many challenges associated with the poor physical and
chemical stability, considerable loss of encapsulated cargo, lack of stimulus responsiveness …

[HTML][HTML] Biofabrication of natural hydrogels for cardiac, neural, and bone Tissue engineering Applications

K Elkhoury, M Morsink, L Sanchez-Gonzalez, C Kahn… - Bioactive materials, 2021 - Elsevier
Natural hydrogels are one of the most promising biomaterials for tissue engineering
applications, due to their biocompatibility, biodegradability, and extracellular matrix …

Exosomal ncRNAs: Novel therapeutic target and biomarker for diabetic complications

YX Xu, SD Pu, X Li, ZW Yu, YT Zhang, XW Tong… - Pharmacological …, 2022 - Elsevier
Exosomes are discoid vesicles with a diameter of 40–160 nm. They are mainly derived from
the multivesicular body formed by the invagination of lysosomal particles in the cell, which …

Hydrogels with electrically conductive nanomaterials for biomedical applications

G Kougkolos, M Golzio, L Laudebat… - Journal of Materials …, 2023 - pubs.rsc.org
Hydrogels, soft 3D materials of cross-linked hydrophilic polymer chains with a high water
content, have found numerous applications in biomedicine because of their similarity to …

Current advances in the use of exosomes, liposomes, and bioengineered hybrid nanovesicles in cancer detection and therapy

A Mukherjee, B Bisht, S Dutta, MK Paul - Acta Pharmacologica Sinica, 2022 - nature.com
Three major approaches of cancer therapy can be enunciated as delivery of biotherapeutics,
tumor image analysis, and immunotherapy. Liposomes, artificial fat bubbles, are long known …

Extracellular vesicles in skin wound healing

D Narauskaitė, G Vydmantaitė, J Rusteikaitė… - Pharmaceuticals, 2021 - mdpi.com
Each year, millions of individuals suffer from a non-healing wound, abnormal scarring, or
injuries accompanied by an infection. For these cases, scientists are searching for new …

Alzheimer's disease: treatment strategies and their limitations

E Passeri, K Elkhoury, M Morsink, K Broersen… - International journal of …, 2022 - mdpi.com
Alzheimer's disease (AD) is the most frequent case of neurodegenerative disease and is
becoming a major public health problem all over the world. Many therapeutic strategies …