Probabilistic genotyping has become widespread. EuroForMix and DNAStatistX are both
based upon maximum likelihood estimation using a γ model, whereas STRmix™ is a …

The deconvolution of DNA mixtures has gathered the attention of forensic DNA scientists for
over two decades. To enhance mixture deconvolution capabilities, a new generation of …

Massively parallel sequencing holds great promise for new possibilities in the field of
forensic genetics, enabling simultaneous analysis of multiple markers as well as offering …

Despite improvements in characterizing stutters of short tandem repeats (STRs), the
relationships among the amounts of stutter variants and the relationships among motifs are …

Insertion/deletion (Indel) genetic markers have special features compared to other forensic-
related markers, such as the low mutation rate and di-allelic markers with length …

The sequencing of STR markers provides additional information present in the underlying
sequence variation that is typically masked by traditional fragment-based genotyping …

Forensic DNA analysis of casework samples using massively parallel sequencing (MPS)
technology requires a system of nomenclature for uniquely labeling sequence-based alleles …

We describe the developmental validation of the probabilistic genotyping software–
STRmix™ NGS–developed for the interpretation of forensic DNA profiles containing …

Massively parallel sequencing (MPS) technologies have revolutionized studies of genomic
variations and transformed DNA analysis in multiple fields. Assays based on MPS must be …

Background Simple Sequence Repeats (SSRs) are short tandem repeats of nucleotide
sequences. It has been shown that SSRs are associated with human diseases and are of …