Triple negative breast cancer and non-small cell lung cancer: Clinical challenges and nano-formulation approaches

S Ghosh, A Javia, S Shetty, D Bardoliwala… - Journal of Controlled …, 2021 - Elsevier
Triple negative breast cancer (TNBC) and non-small cell lung cancer (NSCLC) are amongst
the most aggressive forms of solid tumors. TNBC is highlighted by absence of genetic …

Predictive biomarkers of response to neoadjuvant chemotherapy in breast cancer: current and future perspectives for precision medicine

F Derouane, C van Marcke, M Berlière, A Gerday… - Cancers, 2022 - mdpi.com
Simple Summary Despite the increased use of neoadjuvant chemotherapy in the early
setting of breast cancer, there is a clinical need for predictive markers of response in daily …

Antigen-derived peptides engage the ER stress sensor IRE1α to curb dendritic cell cross-presentation

O Guttman, A Le Thomas, S Marsters… - Journal of Cell …, 2022 - rupress.org
Dendritic cells (DCs) promote adaptive immunity by cross-presenting antigen-based
epitopes to CD8+ T cells. DCs process internalized protein antigens into peptides that enter …

Immune checkpoint inhibitors plus neoadjuvant chemotherapy in early triple-negative breast cancer: a systematic review and meta-analysis

Y Xin, G Shen, Y Zheng, Y Guan, X Huo, J Li, D Ren… - BMC cancer, 2021 - Springer
Purpose Some studies have shown that Immune checkpoint inhibitors (ICIs) have a
favorable efficacy in advanced triple negative breast cancer (TNBC) patients, but the results …

Efficacy and safety of PD-1/PD-L1 inhibitors in triple-negative breast cancer: a systematic review and meta-analysis

M Zhang, J Song, H Yang, F Jin, A Zheng - Acta Oncologica, 2022 - Taylor & Francis
Objective Triple-negative breast cancer (TNBC) is a subtype of breast cancer with a poor
prognosis that seriously threatens women's health. There is still a lack of effective …

The changing clinical spectrum of endocrine adverse events in cancer immunotherapy

S Chiloiro, A Bianchi, A Giampietro, D Milardi… - Trends in Endocrinology …, 2022 - cell.com
Immune checkpoint inhibitors (ICIs) have revolutionized the treatment of several
malignancies, improving patient survival and quality of life. Endocrinopathies have emerged …

Pathogenesis and potential therapeutic targets for triple-negative breast cancer

CJ Li, YDT Tzeng, YH Chiu, HY Lin, MF Hou, PY Chu - Cancers, 2021 - mdpi.com
Simple Summary Breast cancer emergencies have become a rapidly evolving field in
medicine during the last ten years. Carcinogenesis is a multiparametric process that …

TIM3 expression on TILs is associated with poor response to neoadjuvant chemotherapy in patients with locally advanced triple-negative breast cancer

N Cabioglu, S Onder, G Oner, H Karatay, M Tukenmez… - BMC cancer, 2021 - Springer
Background The expression of immune checkpoint receptors (ICRs) on tumor-infiltrating
lymphocytes (TILs) is associated with better response to immunotherapies via immune …

Inhibition of WNT signaling by conjugated microRNA nano-carriers: A new therapeutic approach for treating triple-negative breast cancer a perspective review

M Banerjee, VD Rajeswari - Critical Reviews in Oncology/Hematology, 2023 - Elsevier
Abstract Triple-Negative Breast Cancer is the most aggressive form and accounts the 15%−
25% of all breast cancer. Receptors are absent in triple-negative breast cancer, which …

Seroma after Simple Mastectomy in Breast Cancer—The Role of CD4+ T Helper Cells and the Evidence as a Possible Specific Immune Process

N Pochert, M Schneider, N Ansorge, A Strieder… - International Journal of …, 2022 - mdpi.com
Seroma development after breast cancer surgery is the most common postoperative
complication seen after mastectomy but neither its origin nor its cellular composition is …