Recent advances in engineered materials for immunotherapy‐involved combination cancer therapy

JL Liang, GF Luo, WH Chen, XZ Zhang - Advanced Materials, 2021 - Wiley Online Library
Immunotherapy that can activate immunity or enhance the immunogenicity of tumors has
emerged as one of the most effective methods for cancer therapy. Nevertheless, single …

Recent advancements in polyethyleneimine-based materials and their biomedical, biotechnology, and biomaterial applications

Z Chen, Z Lv, Y Sun, Z Chi, G Qing - Journal of Materials Chemistry B, 2020 - pubs.rsc.org
Cationic polymers, known for their highly positive charges, have historically dominated the
materials used in bioengineering. However, the demand for intelligent systems with high …

Physical activation of innate immunity by spiky particles

J Wang, HJ Chen, T Hang, Y Yu, G Liu, G He… - Nature …, 2018 - nature.com
Microbial biochemicals have been indicated as the primary stimulators of innate immunity,
the first line of the body's defence against infections. However, the influence of topological …

Materials for immunotherapy

CW Shields IV, LLW Wang, MA Evans… - Advanced …, 2020 - Wiley Online Library
Breakthroughs in materials engineering have accelerated the progress of immunotherapy in
preclinical studies. The interplay of chemistry and materials has resulted in improved …

Immunogenic cell death amplified by co-localized adjuvant delivery for cancer immunotherapy

Y Fan, R Kuai, Y Xu, LJ Ochyl, DJ Irvine, JJ Moon - Nano letters, 2017 - ACS Publications
Despite their potential, conventional whole-cell cancer vaccines prepared by freeze–
thawing or irradiation have shown limited therapeutic efficacy in clinical trials. Recent …

Wavelength-encoded laser particles for massively multiplexed cell tagging

N Martino, SJJ Kwok, AC Liapis, S Forward, H Jang… - Nature …, 2019 - nature.com
Large-scale single-cell analyses have become increasingly important given the role of
cellular heterogeneity in complex biological systems. However, no techniques at present …

[HTML][HTML] Supposedly identical microplastic particles substantially differ in their material properties influencing particle-cell interactions and cellular responses

A Ramsperger, J Jasinski, M Völkl, T Witzmann… - Journal of Hazardous …, 2022 - Elsevier
Microplastics and its putative adverse effects on environmental and human health
increasingly gain scientific and public attention. Systematic studies on the effects of …

Neutrophil microvesicles drive atherosclerosis by delivering miR-155 to atheroprone endothelium

I Gomez, B Ward, C Souilhol, C Recarti… - Nature …, 2020 - nature.com
Neutrophils are implicated in the pathogenesis of atherosclerosis but are seldom detected in
atherosclerotic plaques. We investigated whether neutrophil-derived microvesicles may …

Nominally identical microplastic models differ greatly in their particle-cell interactions

S Wieland, AFRM Ramsperger, W Gross… - Nature …, 2024 - nature.com
Due to the abundance of microplastics in the environment, research about its possible
adverse effects is increasing exponentially. Most studies investigating the effect of …

Laser particles with omnidirectional emission for cell tracking

SJ Tang, PH Dannenberg, AC Liapis… - Light: Science & …, 2021 - nature.com
The ability to track individual cells in space over time is crucial to analyzing heterogeneous
cell populations. Recently, microlaser particles have emerged as unique optical probes for …