Shining new light on biological systems: luminescent transition metal complexes for bioimaging and biosensing applications

LCC Lee, KKW Lo - Chemical Reviews, 2024 - ACS Publications
Luminescence imaging is a powerful and versatile technique for investigating cell
physiology and pathology in living systems, making significant contributions to life science …

Bioanalytical methods for hypochlorous acid detection: Recent advances and challenges

R Zhang, B Song, J Yuan - TrAC Trends in Analytical Chemistry, 2018 - Elsevier
Hypochlorous acid (HOCl), a well-known universal disinfectant in clinical practice, plays
important roles in immune systems of animal and human bodies. For understanding the …

HClO‐activated fluorescence and photosensitization from an AIE nanoprobe for image‐guided bacterial ablation in phagocytes

M Wu, W Wu, Y Duan, X Liu, M Wang… - Advanced …, 2020 - Wiley Online Library
Bacteria hiding in host phagocytes are difficult to kill, which can cause phagocyte disorders
resulting in local and systemic tissue damage. Effective accumulation of activatable …

Strategic Design of Luminescent Rhenium (I), Ruthenium (II), and Iridium (III) Complexes as Activity‐Based Probes for Bioimaging and Biosensing

LCC Lee, KKW Lo - Chemistry–An Asian Journal, 2022 - Wiley Online Library
The rapid development of responsive fluorescent probes has advanced optical imaging for
biological research and biomedical applications. Among different sensing strategies, activity …

Determination and imaging of small biomolecules and ions using ruthenium (II) complex-based chemosensors

M Wu, Z Zhang, J Yong, PM Schenk, D Tian… - Metal Ligand …, 2022 - Springer
Luminescence chemosensors are one of the most useful tools for the determination and
imaging of small biomolecules and ions in situ in real time. Based on the unique photo …

Recent advances in fluorescent probes for detection of HOCl and HNO

AH Ashoka, F Ali, R Tiwari, R Kumari, SK Pramanik… - ACS …, 2020 - ACS Publications
It is known that reactive oxygen (ROS) and nitrogen (RNS) species play a diverse role in
various biological processes, such as inflammation, signal transduction, and …

Engineering molecular theranostic probes for antibaterial therapy

X Wang, J Gong, J Wang, F Zhang, Z Mao… - TrAC Trends in Analytical …, 2023 - Elsevier
Bacteria-caused infections have become one of the most notorious diseases threatening
human life and health worldwide. Nonetheless, the increase in antibiotic resistance plus …

Multimetallic transition metal complexes: Luminescent probes for biomolecule sensing, ion detection, imaging and therapeutic application

B Das, P Gupta - Coordination Chemistry Reviews, 2024 - Elsevier
In the past decade, luminescent multimetallic transition metal complexes have become
indispensable tools in biology. They enable versatile applications, detecting biomolecules …

Luminescent probes for hypochlorous acid in vitro and in vivo

S Dong, L Zhang, Y Lin, C Ding, C Lu - Analyst, 2020 - pubs.rsc.org
HClO/ClO− is the most effective antibacterial active oxygen in neutrophils. However, its
excessive existence often leads to the destruction of human physiological mechanisms. In …

Ex Tenebris Lux: Illuminating Reactive Oxygen and Nitrogen Species with Small Molecule Probes

MC Cabello, G Chen, MJ Melville, R Osman… - Chemical …, 2024 - ACS Publications
Reactive oxygen and nitrogen species are small reactive molecules derived from elements
in the air─ oxygen and nitrogen. They are produced in biological systems to mediate …