Biomaterial-based scaffolds are important cues in tissue engineering (TE) applications.
Recent advances in TE have led to the development of suitable scaffold architecture for …

Regenerative engineering converges tissue engineering, advanced materials science, stem
cell science, and developmental biology to regenerate complex tissues such as whole limbs …

Significant progress has been made in the field of cartilage and bone tissue engineering
over the last two decades. As a result, there is real promise that strategies to regenerate …

Osteoarthritis (OA) is a major cause of disability in the adult population. As a progressive
degenerative joint disorder, OA is characterized by cartilage damage, changes in the …

In this work we demonstrate how to print 3D biomimetic hydrogel scaffolds for cartilage
tissue engineering with high cell density (> 10 7 cells ml− 1), high cell viability (85÷ 90%) …

Hyaline cartilage serves as a low-friction and wear-resistant articulating surface in load-
bearing, diarthrodial joints. Unfortunately, as the avascular, alymphatic nature of cartilage …

Osteochondral lesions of the ankle are a more common source of ankle pain than previously
recognized. Although the exact pathophysiology of the condition has not been clearly …

The repair of osteochondral defects requires a tissue engineering approach that aims at
mimicking the physiological properties and structure of two different tissues (cartilage and …

Four decades after the first isolation and characterization of clonogenic bone marrow
stromal cells or mesenchymal stem cells (MSC) in the laboratory of Dr. Alexander …

While a wide variety of approaches to engineering orthopedic tissues have been proposed,
less attention has been paid to the interfaces, the specialized areas that connect two tissues …