Review of the isolation, characterization, biological function, and multifarious therapeutic approaches of exosomes

S Gurunathan, MH Kang, M Jeyaraj, M Qasim, JH Kim - Cells, 2019 - mdpi.com
Exosomes are extracellular vesicles that contain a specific composition of proteins, lipids,
RNA, and DNA. They are derived from endocytic membranes and can transfer signals to …

Recent optical sensing technologies for the detection of various biomolecules

S Kumar, R Singh - Optics & Laser Technology, 2021 - Elsevier
Various optical sensing techniques to develop different biosensors for detection of
biomolecules are summarized here. The identification of biomolecules has led to the major …

Preparation and characterization of extracellular vesicles

S Tiwari, V Kumar, S Randhawa… - American Journal of …, 2021 - Wiley Online Library
Extracellular vesicles (EVs) are heterogeneous membranous vesicles secreted by every cell
type and offer significant potential in therapy and diagnostics. Differential ultracentrifugation …

Methods for the physical characterization and quantification of extracellular vesicles in biological samples

DLM Rupert, V Claudio, C Lässer, M Bally - Biochimica et Biophysica Acta …, 2017 - Elsevier
Background Our body fluids contain a multitude of cell-derived vesicles, secreted by most
cell types, commonly referred to as extracellular vesicles. They have attracted considerable …

Silicon‐based integrated label‐free optofluidic biosensors: latest advances and roadmap

J Wang, MM Sanchez, Y Yin, R Herzer… - Advanced Materials …, 2020 - Wiley Online Library
By virtue of the well‐developed micro‐and nanofabrication technologies and rapidly
progressing surface functionalization strategies, silicon‐based devices have been widely …

Nanohole array plasmonic biosensors: Emerging point-of-care applications

A Prasad, J Choi, Z Jia, S Park, MR Gartia - Biosensors and Bioelectronics, 2019 - Elsevier
Abstract Point-of-care (POC) applications have expanded hugely in recent years and is
likely to continue, with an aim to deliver cheap, portable, and reliable devices to meet the …

Applications of tunable resistive pulse sensing

E Weatherall, GR Willmott - Analyst, 2015 - pubs.rsc.org
Tunable resistive pulse sensing (TRPS) is an experimental technique that has been used to
study and characterise colloidal particles ranging from approximately 50 nm in diameter up …

Critical assessment of relevant methods in the field of biosensors with direct optical detection based on fibers and waveguides using plasmonic, resonance, and …

G Gauglitz - Analytical and Bioanalytical Chemistry, 2020 - Springer
Direct optical detection has proven to be a highly interesting tool in biomolecular interaction
analysis to be used in drug discovery, ligand/receptor interactions, environmental analysis …

Recent advances in optical label-free characterization of extracellular vesicles

M Imanbekova, S Suarasan, Y Lu, S Jurchuk… - …, 2022 - degruyter.com
Extracellular vesicles (EVs) are complex biological nanoparticles endogenously secreted by
all eukaryotic cells. EVs carry a specific molecular cargo of proteins, lipids, and nucleic acids …

Dependence of cancer cell adhesion kinetics on integrin ligand surface density measured by a high-throughput label-free resonant waveguide grating biosensor

N Orgovan, B Peter, S Bősze, JJ Ramsden, B Szabó… - Scientific reports, 2014 - nature.com
A novel high-throughput label-free resonant waveguide grating (RWG) imager biosensor,
the Epic® BenchTop (BT), was utilized to determine the dependence of cell spreading …