The many functions of ESCRTs
M Vietri, M Radulovic, H Stenmark - Nature reviews Molecular cell …, 2020 - nature.com
Cellular membranes can form two principally different involutions, which either exclude or
contain cytosol. The 'classical'budding reactions, such as those occurring during …
contain cytosol. The 'classical'budding reactions, such as those occurring during …
Cellular functions and molecular mechanisms of the ESCRT membrane-scission machinery
L Christ, C Raiborg, EM Wenzel, C Campsteijn… - Trends in biochemical …, 2017 - cell.com
The endosomal sorting complex required for transport (ESCRT) machinery is an assembly of
protein subcomplexes (ESCRT I-III) that cooperate with the ATPase VPS4 to mediate …
protein subcomplexes (ESCRT I-III) that cooperate with the ATPase VPS4 to mediate …
Exosomes and other extracellular vesicles in host–pathogen interactions
An effective immune response requires the engagement of host receptors by pathogen‐
derived molecules and the stimulation of an appropriate cellular response. Therefore, a …
derived molecules and the stimulation of an appropriate cellular response. Therefore, a …
Reverse-topology membrane scission by the ESCRT proteins
The narrow membrane necks formed during viral, exosomal and intra-endosomal budding
from membranes, as well as during cytokinesis and related processes, have interiors that …
from membranes, as well as during cytokinesis and related processes, have interiors that …
Single-virus tracking: from imaging methodologies to virological applications
Uncovering the mechanisms of virus infection and assembly is crucial for preventing the
spread of viruses and treating viral disease. The technique of single-virus tracking (SVT) …
spread of viruses and treating viral disease. The technique of single-virus tracking (SVT) …
HIV-1 assembly, budding, and maturation
WI Sundquist, HG Kräusslich - Cold Spring …, 2012 - perspectivesinmedicine.cshlp.org
A defining property of retroviruses is their ability to assemble into particles that can leave
producer cells and spread infection to susceptible cells and hosts. Virion morphogenesis …
producer cells and spread infection to susceptible cells and hosts. Virion morphogenesis …
Virus budding and the ESCRT pathway
J Votteler, WI Sundquist - Cell host & microbe, 2013 - cell.com
Enveloped viruses escape infected cells by budding through limiting membranes. In the
decade since the discovery that HIV recruits cellular ESCRT (endosomal sorting complexes …
decade since the discovery that HIV recruits cellular ESCRT (endosomal sorting complexes …
Molecular mechanisms of the membrane sculpting ESCRT pathway
WM Henne, H Stenmark… - Cold Spring Harbor …, 2013 - cshperspectives.cshlp.org
The endosomal sorting complexes required for transport (ESCRT) drive multivesicular body
(MVB) biogenesis and cytokinetic abscission. Originally identified through genetics and cell …
(MVB) biogenesis and cytokinetic abscission. Originally identified through genetics and cell …
Multivesicular body morphogenesis
PI Hanson, A Cashikar - Annual review of cell and …, 2012 - annualreviews.org
Multivesicular bodies (MVBs) are unique organelles in the endocytic pathway that contain
vesicles in their lumen. Sorting and incorporation of material into such vesicles is a critical …
vesicles in their lumen. Sorting and incorporation of material into such vesicles is a critical …
Structures, functions, and dynamics of ESCRT-III/Vps4 membrane remodeling and fission complexes
J McCullough, A Frost… - Annual review of cell and …, 2018 - annualreviews.org
The endosomal sorting complexes required for transport (ESCRT) pathway mediates
cellular membrane remodeling and fission reactions. The pathway comprises five core …
cellular membrane remodeling and fission reactions. The pathway comprises five core …