Human papillomaviruses: diversity, infection and host interactions

AA McBride - Nature Reviews Microbiology, 2022 - nature.com
Human papillomaviruses (HPVs) are an ancient and highly successful group of viruses that
have co-evolved with their host to replicate in specific anatomical niches of the stratified …

NAD+ metabolism: pathophysiologic mechanisms and therapeutic potential

N Xie, L Zhang, W Gao, C Huang, PE Huber… - Signal transduction and …, 2020 - nature.com
Nicotinamide adenine dinucleotide (NAD+) and its metabolites function as critical regulators
to maintain physiologic processes, enabling the plastic cells to adapt to environmental …

The oral microbiome and cancer

M Irfan, RZR Delgado, J Frias-Lopez - Frontiers in immunology, 2020 - frontiersin.org
There is mounting evidence that members of the human microbiome are highly associated
with a wide variety of cancer types. Among oral cancers, oral squamous cell carcinoma …

The global landscape of EBV-associated tumors

C Shannon-Lowe, A Rickinson - Frontiers in oncology, 2019 - frontiersin.org
Epstein-Barr virus (EBV), a gamma-1 herpesvirus, is carried as a life-long asymptomatic
infection by the great majority of individuals in all human populations. Yet this seemingly …

Molecular Mechanism of Helicobacter pylori-Induced Gastric Cancer

M Alipour - Journal of gastrointestinal cancer, 2021 - Springer
Introduction Various types of cancers threaten human life. The role of bacteria in causing
cancer is controversial, but it has been determined that the Helicobacter pylori infection is …

Innate immunity and cancer pathophysiology

L Maiorino, J Daßler-Plenker, L Sun… - Annual Review of …, 2022 - annualreviews.org
Chronic inflammation increases the risk of several cancers, including gastric, colon, and
hepatic cancers. Conversely, tumors, similar to tissue injury, trigger an inflammatory …

Modulating the microbiome to improve therapeutic response in cancer

JL McQuade, CR Daniel, BA Helmink… - The Lancet …, 2019 - thelancet.com
Although novel therapies, including immunotherapy, have dramatically improved outcomes
for many patients with cancer, overall outcomes are heterogeneous and existing biomarkers …

Cancer metastasis: molecular mechanisms and clinical perspectives

SU Khan, K Fatima, F Malik, H Kalkavan… - Pharmacology & …, 2023 - Elsevier
Metastatic progression combined with non-responsiveness towards systemic therapy often
shapes the course of disease for cancer patients and commonly determines its lethal …

Persistent human papillomavirus infection

AN Della Fera, A Warburton, TL Coursey, S Khurana… - Viruses, 2021 - mdpi.com
Simple Summary The success of HPV as an infectious agent lies not within its ability to
cause disease, but rather in the adeptness of the virus to establish long-term persistent …

An overview of cancer treatment modalities

Z Abbas, S Rehman - Neoplasm, 2018 - books.google.com
Cancer is a global issue majorly affecting developing countries. According to a survey, 63%
of deaths due to cancer are reported from developing countries. There are different …