Over the last decade, animal models of atopic dermatitis (AD) have received increasing
attention. They include NC/Nga mice, a hapten-induced mouse model, and transgenic and …

We have examined the expression of chemokines and their receptors in the atopic dermatitis–
like (AD-like) lesions of NC/Nga mice. Such lesions develop when the mice are kept in …

Pruritus is an important symptom in atopic dermatitis (AD), but the major pruritogen have not
been identified. NC/Nga mice, spontaneously develop an eczematous AD‐like skin lesion …

Abstract Paramylon is a β-1, 3-D-glucan isolated from Euglena gracilis Z. This study was
designed to evaluate the suppressive effects of the oral administration of paramylon on the …

IgE hyperproduction frequently observed in patients with atopic dermatitis (AD) may greatly
contribute to the pathogenesis of AD, but its mechanisms are still unclear. NC/Nga mice …

Background The pathogenesis and aetiology of atopic dermatitis (AD) remain unclear.
Establishment of suitable animal models should aid elucidation of the pathogenesis and …

We investigated the spontaneous scratching by NC/Nga mice to design a new method for
evaluating the itch of subjects with atopic dermatitis. The numbers of scratchings in various …

抄録 The effect of tacrolimus hydrate (FK506) ointment on spontaneous dermatitis in NC/Nga
(NC) mice was examined. FK506 ointment (0.1–1%) suppressed the development of …

The present study was conducted to investigate the effects of Baicalein (BE), which is
hydrolyzed product of Baicalin (BA), on atopic dermatitis (AD). AD was induced in NC/Nga …

Background: Atopic dermatitis (AD) is a chronic relapsing inflammation usually observed in
patients with an individual or a familial history of atopic diseases, precipitated by …