Tumor innervation: peripheral nerves take control of the tumor microenvironment
In recent decades, cancer research has expanded exponentially beyond the study of
abnormally dividing cells to include complex and extensive heterotypic interactions between …
abnormally dividing cells to include complex and extensive heterotypic interactions between …
The neuropeptide Y system: pathophysiological and therapeutic implications in obesity and cancer
L Zhang, MS Bijker, H Herzog - Pharmacology & therapeutics, 2011 - Elsevier
The neuropeptide Y (NPY) system–comprising of neuropeptide Y, peptide YY, pancreatic
polypeptide and the corresponding Y receptors through which they act (Y1, Y2, Y4, Y5 and …
polypeptide and the corresponding Y receptors through which they act (Y1, Y2, Y4, Y5 and …
The proteome of primary prostate cancer
D Iglesias-Gato, P Wikström, S Tyanova, C Lavallee… - European urology, 2016 - Elsevier
Background Clinical management of the prostate needs improved prognostic tests and
treatment strategies. Because proteins are the ultimate effectors of most cellular reactions …
treatment strategies. Because proteins are the ultimate effectors of most cellular reactions …
Neuropeptide Y is produced in visceral adipose tissue and promotes proliferation of adipocyte precursor cells via the Y1 receptor
Neuropeptide Y (NPY) is synthesized in neural tissue of the central and peripheral nervous
systems and has a number of important functions besides regulating appetite and energy …
systems and has a number of important functions besides regulating appetite and energy …
Neuropeptide Y peptide family and cancer: Antitumor therapeutic strategies
ML Sánchez, FD Rodríguez, R Coveñas - International Journal of …, 2023 - mdpi.com
Currently available data on the involvement of neuropeptide Y (NPY), peptide YY (PYY), and
pancreatic polypeptide (PP) and their receptors (YRs) in cancer are updated. The structure …
pancreatic polypeptide (PP) and their receptors (YRs) in cancer are updated. The structure …
Targeting neuropeptide receptors for cancer imaging and therapy: perspectives with bombesin, neurotensin, and neuropeptide-Y receptors
Receptors for some regulatory peptides are highly expressed in tumors. Selective
radiolabeled peptides can bind with high affinity and specificity to these receptors and …
radiolabeled peptides can bind with high affinity and specificity to these receptors and …
Depression-induced neuropeptide Y secretion promotes prostate cancer growth by recruiting myeloid cells
Y Cheng, XY Tang, YX Li, DD Zhao, QH Cao… - Clinical Cancer …, 2019 - AACR
Purpose: Psychologic depression has been shown to dysregulate the immune system and
promote tumor progression. The aim of this study is to investigate how psychologic …
promote tumor progression. The aim of this study is to investigate how psychologic …
6-Shogaol inhibits breast and colon cancer cell proliferation through activation of peroxisomal proliferator activated receptor γ (PPARγ)
6-Shogaol has been shown to possess many antitumor properties including inhibition of
cancer cell growth, inhibition of cancer metastasis, induction of apoptosis in cancer cells and …
cancer cell growth, inhibition of cancer metastasis, induction of apoptosis in cancer cells and …
NPY receptors in human cancer: a review of current knowledge
M Körner, JC Reubi - Peptides, 2007 - Elsevier
Many peptide hormone receptors are over-expressed in human cancer, permitting an in vivo
targeting of tumors for diagnostic and therapeutic purposes. NPY receptors are novel and …
targeting of tumors for diagnostic and therapeutic purposes. NPY receptors are novel and …
Neuropeptide Y receptors: a promising target for cancer imaging and therapy
Neuropeptide Y (NPY) was first identified from porcine brain in 1982, and plays its biological
functions in humans through NPY receptors (Y1, Y2, Y4 and Y5). NPY receptors are known …
functions in humans through NPY receptors (Y1, Y2, Y4 and Y5). NPY receptors are known …