Lactate, a byproduct of glycolysis, was considered as a metabolic waste until identified by
studies on the Warburg effect. Increasing evidence elucidates that lactate functions as …

Motor Neuron Diseases (MND) are neurological disorders characterized by a loss of varying
motor neurons resulting in decreased physical capabilities. Current research is focused on …

Abstract Glucose-6-phosphate dehydrogenase (G6PDH) catalyses the rate limiting first step
of the oxidative part of the pentose phosphate pathway (PPP), which has a crucial function in …

Motoneurons are one of the most energy-demanding cell types and a primary target in
Amyotrophic lateral sclerosis (ALS), a debilitating and lethal neurodegenerative disorder …

A moderating hub between resting state networks (RSNs) and the medial temporal lobe
(MTL) is the parahippocampal cortex (PHC). Abnormal activity has been reported in …

Nervous system diseases present significant challenges to the neuroscience community due
to ethical and practical constraints that limit access to appropriate research materials …

The pentose phosphate pathway (PPP) is one of three major pathways involved in glucose
metabolism, which is regulated by glucose-6-phosphate dehydrogenase (G6PD) controls …

Misfolded species of superoxide dismutase 1 (SOD1) are associated with increased death in
amyotrophic lateral sclerosis (ALS) models compared to insoluble protein aggregates. The …

Misfolded soluble trimeric species of superoxide dismutase 1 (SOD1) have been linked to
increased cell death in neuron-like cell models and greater disease severity in amyotrophic …

Motor Neuron Diseases (MND) are neurological disorders characterized by a loss of varying
motor neurons resulting in decreased physical capabilities. Current research is focused on …