NUMB, a plasma membrane-associated protein originally described in Drosophila, is
involved in determining cell function and fate during early stages of development. It is …

Simple Summary Forced molting refers to the systemic stress response of laying hens
caused by some externally imposed artificial measures (such as starvation), resulting in …

Ubiquitin-proteasome system (UPS) dysfunction is associated with the pathology of a wide
range of human diseases, including myopathies and muscular atrophy. However, the …

Excessive abdominal fat deposition negatively impacts poultry meat production and carcass
yield. Identification of novel adipogenesis regulators may help improve production …

Here, we investigated the mechanisms by which aging-related reductions of the levels of
Numb in skeletal muscle fibers contribute to loss of muscle strength and power, two critical …

Desmin and Vimentin are major intermediate filaments at the Z-disc and play significant
roles in sarcomere architecture and signaling transduction. Abnormal expression of …

New Findings What is the central question of this study? Do Notch, Numb and Numb‐like
expression change in human skeletal muscle after exercise‐induced muscle damage? What …

Background The existing literature regarding the association between muscle strength and
cardiovascular disease (CVD) and all-cause mortality relies mostly on a single …

Skeletal muscle undergoes rapid and extensive atrophy following nerve transection though
the underlying mechanisms remain incompletely understood. We previously showed …

Epigenetic modifications play an important role in regulating animal adaptation to external
stress. To explore how DNA methylation regulates the expression levels of related genes …