Histone methylation can occur at various sites in histone proteins, primarily on lysine and
arginine residues, and it can be governed by multiple positive and negative regulators, even …

Neuroblastoma is a developmental tumor of young children arising from the embryonic
sympathoadrenal lineage of the neural crest. Neuroblastoma is the primary cause of death …

After induction and specification in the ectoderm, at the border of the neural plate, the neural
crest (NC) population leaves its original territory through a delamination process. Soon …

The neural crest (NC) is a highly migratory multipotent cell population that forms at the
interface between the neuroepithelium and the prospective epidermis of a developing …

Many craniofacial disorders are caused by heterozygous mutations in general regulators of
housekeeping cellular functions such as transcription or ribosome biogenesis,. Although it is …

Most human cancers harbor mutations in the gene encoding p53. As a result, research on
p53 in the past few decades has focused primarily on its role as a tumor suppressor. One …

The epithelial–mesenchymal transition (EMT) plays a pivotal role in the differentiation of
vertebrates and is critically important in tumorigenesis. Using this evolutionarily conserved …

This review on acne transcriptomics allows for deeper insights into the pathogenesis of acne
and isotretinoin's mode of action. Puberty-induced insulin-like growth factor 1 (IGF-1), insulin …

CHARGE syndrome is a multiple anomaly disorder in which patients present with a variety of
phenotypes, including ocular coloboma, heart defects, choanal atresia, retarded growth and …

We review here some of the historical highlights in exploratory studies of the vertebrate
embryonic structure known as the neural crest. The study of the molecular properties of the …