Application of artificial intelligence techniques for monkeypox: a systematic review
Monkeypox or Mpox is an infectious virus predominantly found in Africa. It has spread to
many countries since its latest outbreak. Symptoms such as headaches, chills, and fever are …
many countries since its latest outbreak. Symptoms such as headaches, chills, and fever are …
Emergence of monkeypox: a worldwide public health crisis
The human monkeypox virus (MPV), a zoonotic illness that was hitherto solely prevalent in
Central and West Africa, has lately been discovered to infect people all over the world and …
Central and West Africa, has lately been discovered to infect people all over the world and …
Structure-based design of promising natural products to inhibit thymidylate kinase from Monkeypox virus and validation using free energy calculations
Monkeypox (MPXV) is a globally growing public health concern with 80,328 active cases
and 53 deaths have been reported. No specific vaccine or drug is available for the treatment …
and 53 deaths have been reported. No specific vaccine or drug is available for the treatment …
Flavonoids as dual-target inhibitors against α-glucosidase and α-amylase: a systematic review of in vitro studies
Diabetes mellitus remains a major global health issue, and great attention is directed at
natural therapeutics. This systematic review aimed to assess the potential of flavonoids as …
natural therapeutics. This systematic review aimed to assess the potential of flavonoids as …
In-silico investigation of E8 surface protein of the monkeypox virus to identify potential therapeutic agents
S Podduturi, D Vemula, S Singothu… - Journal of Biomolecular …, 2024 - Taylor & Francis
The re-emergence of the monkeypox virus (MPXV) in 2022 has become a global issue. The
virus was first found in Denmark in 1958. The first human MPXV disease was reported in …
virus was first found in Denmark in 1958. The first human MPXV disease was reported in …
Exploring Monkeypox: Prospects for therapeutics through computational-aided drug discovery
DB Grajales, S Kar - Molecular Diversity, 2023 - Springer
Monkeypox virus (MPXV) has emerged as a significant public health concern due to its
potential for human transmission and its severe clinical manifestations. This review …
potential for human transmission and its severe clinical manifestations. This review …
Machine learning and classical MD simulation to identify inhibitors against the P37 envelope protein of monkeypox virus
Monkeypox virus (MPXV) outbreak is a serious public health concern that requires
international attention. P37 of MPXV plays a pivotal role in DNA replication and acts as one …
international attention. P37 of MPXV plays a pivotal role in DNA replication and acts as one …
Computational investigations of potential inhibitors of monkeypox virus envelope protein E8 through molecular docking and molecular dynamics simulations
Abstract The World Health Organization (WHO) has declared the monkeypox outbreak a
public health emergency, as there is no specific therapeutics for monkeypox virus (MPXV) …
public health emergency, as there is no specific therapeutics for monkeypox virus (MPXV) …
Trends and Applications in Computationally Driven Drug Repurposing
L Pinzi, G Rastelli - International Journal of Molecular Sciences, 2023 - mdpi.com
Drug repurposing is a widely used approach originally developed to aid in the identification
of new uses of already existing drugs outside the scope of the original medical indication [1] …
of new uses of already existing drugs outside the scope of the original medical indication [1] …
In silico approach to identify novel allosteric intracellular antagonist for blocking the interleukin-8/CXCR2 receptor signaling pathway
TTN Tran, QH Tran, CQ Duong… - Journal of …, 2023 - Taylor & Francis
The role of interleukin-8 (IL-8) and its receptor CXCR2 in inflammatory responses and tumor
development and progression has been well documented. Our study aims to discover novel …
development and progression has been well documented. Our study aims to discover novel …