Therapeutic benefits of rutin and its nanoformulations

R Negahdari, S Bohlouli, S Sharifi… - Phytotherapy …, 2021 - Wiley Online Library
Background Rutin as a natural flavonoid compound has revealed an extensive range of
therapeutic potentials. Purpose The current paper is focused on the numerous studies on …

Targeting multiple signaling pathways in cancer: The rutin therapeutic approach

Z Nouri, S Fakhri, K Nouri, CE Wallace, MH Farzaei… - Cancers, 2020 - mdpi.com
Multiple dysregulated signaling pathways are implicated in the pathogenesis of cancer. The
conventional therapies used in cancer prevention/treatment suffer from low efficacy …

An intriguing approach toward antibacterial activity of green synthesized Rutin-templated mesoporous silica nanoparticles decorated with nanosilver

M Abbasi, R Gholizadeh, SR Kasaee, A Vaez… - Scientific reports, 2023 - nature.com
In recent years, mesoporous silica nanoparticles (MSNs) have been applied in various
biomedicine fields like bioimaging, drug delivery, and antibacterial alternatives. MSNs could …

Antibacterial activity of some flavonoids and organic acids widely distributed in plants

A Adamczak, M Ożarowski, TM Karpiński - Journal of clinical medicine, 2019 - mdpi.com
Among natural substances widespread in fruits, vegetables, spices, and medicinal plants,
flavonoids and organic acids belong to the promising groups of bioactive compounds with …

In silico Screening of Natural Compounds as Potential Inhibitors of SARS-CoV-2 Main Protease and Spike RBD: Targets for COVID-19

DM Teli, MB Shah, MT Chhabria - Frontiers in molecular biosciences, 2021 - frontiersin.org
Historically, plants have been sought after as bio-factories for the production of diverse
chemical compounds that offer a multitude of possibilities to cure diseases. To combat the …

Rutin ameliorates inflammation and improves metabolic function: A comprehensive analysis of scientific literature

N Muvhulawa, PV Dludla, K Ziqubu… - Pharmacological …, 2022 - Elsevier
Chronic inflammation remains an essential complication in the pathogenesis and
aggravation of metabolic diseases. There is a growing interest in the use of medicinal plants …

Dietary phenolic compounds: their health benefits and association with the gut microbiota

Y Matsumura, M Kitabatake, S Kayano, T Ito - Antioxidants, 2023 - mdpi.com
Oxidative stress causes various diseases, such as type II diabetes and dyslipidemia, while
antioxidants in foods may prevent a number of diseases and delay aging by exerting their …

Fungal endophytes as efficient sources of plant-derived bioactive compounds and their prospective applications in natural product drug discovery: Insights, avenues …

A Singh, DK Singh, RN Kharwar, JF White, SK Gond - Microorganisms, 2021 - mdpi.com
Fungal endophytes are well-established sources of biologically active natural compounds
with many producing pharmacologically valuable specific plant-derived products. This …

A review of the role of flavonoids in peptic ulcer (2010–2020)

C Serafim, ME Araruna, EA Júnior, M Diniz… - Molecules, 2020 - mdpi.com
Peptic ulcers are characterized by erosions on the mucosa of the gastrointestinal tract that
may reach the muscle layer. Their etiology is multifactorial and occurs when the balance …

[HTML][HTML] Extraction of phenolic compounds from grape pomace using ohmic heating: Chemical composition, bioactivity and bioaccessibility

P Ferreira-Santos, C Nobre, RM Rodrigues… - Food Chemistry, 2024 - Elsevier
This study addresses the effectiveness of ohmic heating technology (OH) for the sustainable
recovery of phenolic compounds from Grape Pomace (GP) by hydroethanolic extraction. GP …