Amphetamine-related drugs neurotoxicity in humans and in experimental animals: Main mechanisms

R Moratalla, A Khairnar, N Simola, N Granado… - Progress in …, 2017 - Elsevier
Amphetamine-related drugs, such as 3, 4-methylenedioxymethamphetamine (MDMA) and
methamphetamine (METH), are popular recreational psychostimulants. Several preclinical …

The pharmacology and clinical pharmacology of 3, 4-methylenedioxymethamphetamine (MDMA,“ecstasy”)

AR Green, AO Mechan, JM Elliott, E O'Shea… - Pharmacological …, 2003 - ASPET
The amphetamine derivative (±)-3, 4-methylenedioxymethamphetamine (MDMA, ecstasy) is
a popular recreational drug among young people, particularly those involved in the dance …

Toxic leukoencephalopathy

CM Filley… - New England Journal of …, 2001 - Mass Medical Soc
Leukoencephalopathy is a structural alteration of cerebral white matter in which myelin
suffers the most damage. Toxic leukoencephalopathy may be caused by exposure to a wide …

Neurotoxicity of MDMA: main effects and mechanisms

G Costa, K Gołembiowska - Experimental neurology, 2022 - Elsevier
Preclinical and clinical studies indicate that 3, 4-methylenedioxymethamphetamine
(MDMA;'ecstasy'), in addition to having abuse potential, may elicit acute and persistent …

Neurotoxicity of methamphetamine and 3, 4-methylenedioxymethamphetamine

LE Halpin, SA Collins, BK Yamamoto - Life sciences, 2014 - Elsevier
Amphetamines are a class of psychostimulant drugs that are widely abused for their
stimulant, euphoric, empathogenic and hallucinogenic properties. Many of these effects …

Amphetamine toxicities: classical and emerging mechanisms

BK Yamamoto, A Moszczynska… - Annals of the New York …, 2010 - Wiley Online Library
The drugs of abuse, methamphetamine and MDMA, produce long‐term decreases in
markers of biogenic amine neurotransmission. These decreases have been traditionally …

Molecular and cellular mechanisms of ecstasy-induced neurotoxicity: an overview

JP Capela, H Carmo, F Remião, ML Bastos… - Molecular …, 2009 - Springer
Abstract “Ecstasy”[(±)-3, 4-methylenedioxymethamphetamine, MDMA, XTC, X, E] is a
psychoactive recreational hallucinogenic substance and a major worldwide drug of abuse …

Acute psychological effects of 3, 4-methylenedioxymethamphetamine (MDMA,“Ecstasy”) are attenuated by the serotonin uptake inhibitor citalopram

ME Liechti, C Baumann, A Gamma… - …, 2000 - Elsevier
3, 4-Methylenedioxymethamphetamine (MDMA,“Ecstasy”) is a recreational drug that has
been shown to release serotonin (5-HT) and dopamine (DA) in animals. The effect of MDMA …

Recreational Ecstasy/MDMA, the serotonin syndrome, and serotonergic neurotoxicity

AC Parrott - Pharmacology Biochemistry and Behavior, 2002 - Elsevier
The ring-substituted amphetamine derivative 3, 4-methylenedioxymethamphetamine
(MDMA) or “Ecstasy” is widely used a recreational drug. It stimulates the release and inhibits …

Human psychopharmacology of Ecstasy (MDMA): a review of 15 years of empirical research

AC Parrott - Human Psychopharmacology: Clinical and …, 2001 - Wiley Online Library
Abstract MDMA (3, 4‐methylenedioxymethamphetamine) or 'Ecstasy'was scheduled as an
illegal drug in 1986, but since then its recreational use has increased dramatically. This …