Cancer ranks as one of the deadliest diseases worldwide. The high mortality rate associated
with cancer is partially due to the lack of reliable early detection methods and/or inaccurate …

Long non-coding RNAs (lncRNAs) are emerging as new players in the cancer paradigm
demonstrating potential roles in both oncogenic and tumor suppressive pathways. These …

Maternal-offspring interactions in mammals involve both cooperation and conflict. The fetus
has evolved ways to manipulate maternal physiology to enhance placental nutrient transfer …

The H19 gene produces a non‐coding RNA, which is abundantly expressed during
embryonic development and down‐regulated after birth. Although this gene was discovered …

Long noncoding RNAs are emerging as key players in various fundamental biological
processes. We highlight the varied molecular mechanisms by which lncRNAs modulate …

BACKGROUND The placenta is of utmost importance for intrauterine fetal development and
growth. Deregulation of placentation can lead to adverse outcomes for both mother and …

DNA methylation is a major epigenetic modification in the genomes of higher eukaryotes. In
vertebrates, DNA methylation occurs predominantly on the CpG dinucleotide, and …

Highlights•Long non-coding RNAs (lncRNAs) are a heterogeneous class of RNAs.•By acting
as signal, guide, decoy or scaffold, lncRNAs are involved in several types of diseases …

Imprinted genes play crucial roles in mammalian development and disruption of their
expression is associated with many human disorders including tumourigenesis; yet, the …

Genomic imprinting causes the expression of an allele depending on its parental origin. In
plants, most imprinted genes have been identified in Arabidopsis endosperm, a transient …