Collecting duct principal cell transport processes and their regulation

D Pearce, R Soundararajan, C Trimpert… - Clinical journal of the …, 2015 - journals.lww.com
The principal cell of the kidney collecting duct is one of the most highly regulated epithelial
cell types in vertebrates. The effects of hormonal, autocrine, and paracrine factors to regulate …

[HTML][HTML] Human aquaporins: regulators of transcellular water flow

RE Day, P Kitchen, DS Owen, C Bland… - … et Biophysica Acta (BBA …, 2014 - Elsevier
Background Emerging evidence supports the view that (AQP) aquaporin water channels are
regulators of transcellular water flow. Consistent with their expression in most tissues, AQPs …

[HTML][HTML] Molecular mechanisms governing aquaporin relocalisation

A Markou, L Unger, M Abir-Awan, A Saadallah… - … et Biophysica Acta (BBA …, 2022 - Elsevier
The aquaporins (AQPs) form a family of integral membrane proteins that facilitate the
movement of water across biological membrane by osmosis, as well as facilitating the …

Physiology and pathophysiology of the calcium-sensing receptor in the kidney

D Riccardi, EM Brown - American Journal of Physiology …, 2010 - journals.physiology.org
The extracellular calcium-sensing receptor (CaSR) plays a major role in the maintenance of
a physiological serum ionized calcium (Ca2+) concentration by regulating the circulating …

Aquaporins at a glance

AS Verkman - Journal of cell science, 2011 - journals.biologists.com
Cell Science at a Glance 2107 enhanced osmotic compared with diffusional water
permeability, which suggested water movement through a pore-like pathway. The molecular …

Treating lysosomal storage diseases with pharmacological chaperones: from concept to clinics

G Parenti - EMBO molecular medicine, 2009 - embopress.org
Lysosomal storage diseases (LSDs) are a group of genetic disorders due to defects in any
aspect of lysosomal biology. During the past two decades, different approaches have been …

Mechanisms of protein kinase A anchoring

P Skroblin, S Grossmann, G Schäfer… - International review of …, 2010 - Elsevier
The second messenger cyclic adenosine monophosphate (cAMP), which is produced by
adenylyl cyclases following stimulation of G-protein-coupled receptors, exerts its effect …

[HTML][HTML] Structural insights into eukaryotic aquaporin regulation

S Törnroth-Horsefield, K Hedfalk, G Fischer… - FEBS letters, 2010 - Elsevier
Aquaporin-mediated water transport across cellular membranes is an ancient, ubiquitous
mechanism within cell biology. This family of integral membrane proteins includes both …

Molecular mechanisms regulating aquaporin-2 in kidney collecting duct

HJ Jung, TH Kwon - American Journal of Physiology-Renal …, 2016 - journals.physiology.org
The kidney collecting duct is an important renal tubular segment for regulation of body water
homeostasis and urine concentration. Water reabsorption in the collecting duct principal …

[HTML][HTML] Alleviating effects and mechanisms of action of large-leaf yellow tea drinking on diabetes and diabetic nephropathy in mice

G Zhao, J Teng, R Dong, Q Ban, L Yang, K Du… - Food Science and …, 2023 - Elsevier
Our previous study found that large-leaf yellow tea (LYT) had interesting hypoglycemic
activity in high-fat diet-induced obese mice and highly safety in healthy mice. To study the …