Two-dimensional infrared (2D IR) spectroscopy has recently emerged as a powerful tool
with applications in many areas of scientific research. The inherent high time resolution …

Proteins, enzymes, and other biological molecules undergo structural dynamics as an
intrinsic part of their biological functions. While many biological processes occur on the …

The advent of laser-based sources of ultrafast infrared pulses has extended the study of very
fast molecular dynamics to the observation of processes manifested through their effects on …

Utilization of the renewable solar fuel based on a perylenetetracarboxylic acid diimide
(PTCDI)–semiconductor composite represents an effective method to solve the energy crisis; …

Ultrafast two-dimensional infrared (2D IR) vibrational echo spectroscopy has proven broadly
useful for studying molecular dynamics in solutions. Here, we extend the technique to …

Protein dynamics and interactions in myoglobin (Mb) were characterized via two vibrational
dynamics labels (VDLs): a genetically incorporated site-specific azide (Az) bearing …

A nitrile-labeled amino acid, p-cyanophenylalanine, is introduced near the active site of the
semisynthetic enzyme ribonuclease S to serve as a probe of protein dynamics and …

The center line slope (CLS) method is often used to extract the frequency-frequency
correlation function (FFCF) from 2D IR spectra to delineate dynamics and to identify …

Proteins are complex, heterogeneous macromolecules that exist as ensembles of
interconverting states on a complex energy landscape. A complete, molecular-level …

The calcium sensor protein calmodulin is ubiquitous among eukaryotes. It translates
intracellular Ca2+ influx (by a decrease of conformational flexibility) into increased target …