Several nutrition, food and dietary compounds have been suggested to be involved in the
onset and maintenance of depressive disorders and in the severity of depressive symptoms …

Macrophages and their counterparts in the central nervous system, the microglia, detect and
subsequently clear microbial pathogens and injured tissue. These phagocytic cells alter and …

Recent compelling evidence has suggested that the glutamate system is a primary mediator
of psychiatric pathology and also a target for rapid-acting antidepressants. Clinical research …

Impaired hippocampal synaptic plasticity contributes to cognitive impairment in Huntington's
disease (HD). However, the molecular basis of such synaptic plasticity defects is not fully …

Studies have pointed to a relationship between MAPK kinase (MEK) signaling and the
behavioral effects of antidepressant drugs. So, in the present study we examined the …

The plasticity of excitatory synapses is an essential brain process involved in cognitive
functions, and dysfunctions of such adaptations have been linked to psychiatric disorders …

Antidepressant drugs are a standard biological treatment for various neuropsychiatric
disorders, yet relatively little is known about their electrophysiologic and synaptic effects on …

Aims Tilianin, a naturally occurring flavonoid glycoside, possesses versatile biological
activities including antioxidant, anti-inflammatory, energy collecting and anti-hypoxic effects …

Tilianin is a naturally occurring phenolic compound with a cardioprotective effect against
myocardial ischemia/reperfusion injury (MIRI). The aim of our study was to determine the …

Mutations in the X-linked cyclin-dependent kinase-like 5 (CDKL5) gene cause a complex
neurological disorder, characterized by infantile seizures, impairment of cognitive and motor …